Evidence map›Paper›PMID 34061243›Full record

ArticleCancer immunology, immunotherapy : CII2022

STAT3 is over-activated within CD163

Morten N Andersen, Niels F Andersen, Kristina L Lauridsen, Anders Etzerodt, Boe S Sorensen, Niels Abildgaard, Trine Plesner, Marianne Hokland, Holger J Møller

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Morten N AndersenDepartment of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark. morten@biomed.au.dk.ORCID http://orcid.org/0000-0003-0820-7789
Niels F AndersenDepartment of Hematology, Aarhus University Hospital, Aarhus, Denmark.
Kristina L LauridsenDepartment of Histopathology, Aarhus University Hospital, Aarhus, Denmark.
Anders EtzerodtDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Boe S SorensenDepartment of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.
Niels AbildgaardDepartment of Hematology, Odense University Hospital, Odense, Denmark.
Trine PlesnerDepartment of Histopathology, Aarhus University Hospital, Aarhus, Denmark.
Marianne HoklandDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Holger J MøllerDepartment of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.
Aarhus University Hospital · DKAarhus University · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumour-associated macrophages (TAMs) support cancer cell survival and suppress anti-tumour immunity. Tumour infiltration by CD163

Indexed as

AgedAntigens, CDAntigens, Differentiation, MyelomonocyticBone MarrowBone Marrow CellsCase-Control StudiesCD163 AntigenFemaleHumansImmunosuppression TherapyImmunosuppressive AgentsInflammationMacrophagesMaleMiddle AgedMonoclonal Gammopathy of Undetermined SignificanceAntigens, CDAntigens, Differentiation, MyelomonocyticCD163 AntigenImmunosuppressive AgentsReceptors, Cell SurfaceSTAT3 protein, humanSTAT3 Transcription FactorBone marrow microenvironmentCD163MacrophageMGUSMultiple myelomaSTAT3

Identifiers

PMID34061243
PMCPMC10992042
OpenAlexW3165118104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.