Evidence map›Paper›PMID 34061030›Full record

ArticleeLife2021

Handling of intracellular K

Shreyas Bhat, Marco Niello, Klaus Schicker, Christian Pifl, Harald H Sitte, Michael Freissmuth, Walter Sandtner

Open access · goldAbstract readComparative StudyVideo-Audio Media
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. Cytosolic KJournal of chemical theory and computation · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Identification of the potassium-binding site in serotonin transporter.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Exploring the KeLife · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Two Lignan Glycosides fromPharmaceuticals (Basel, Switzerland) · 2022
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shreyas Bhat *Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-7019-9180
Marco Niello *Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Klaus SchickerDivision of Neurophysiology and Neuropharmacology, Centre for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Christian PiflCenter for Brain Research, Medical University of Vienna, Vienna, Austria.
Harald H SitteInstitute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-1339-7444
Michael FreissmuthInstitute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Walter SandtnerInstitute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-3637-260X
Medical University of Vienna · AT

Funding

Austrian Science Fund FWF P 31599Austrian Science Fund FWF W 1232
6 · The paper itself

Abstract

The concentrative power of the transporters for dopamine (DAT), norepinephrine (NET), and serotonin (SERT) is thought to be fueled by the transmembrane Na

Indexed as

Aniline CompoundsBiological Transport, ActiveDopamine Plasma Membrane Transport ProteinsHEK293 CellsHumansKineticsMembrane PotentialsMicroscopy, FluorescenceMicroscopy, VideoModels, BiologicalNorepinephrine Plasma Membrane Transport ProteinsPotassiumPyridinium CompoundsSerotonin Plasma Membrane Transport Proteins4-(4-(dimethylamino)phenyl)-1-methylpyridiniumAniline CompoundsDopamine Plasma Membrane Transport ProteinsNorepinephrine Plasma Membrane Transport ProteinsPotassiumPyridinium CompoundsSerotonin Plasma Membrane Transport ProteinsSLC6A2 protein, humanSLC6A4 protein, humandopamine transporterhumanintracellular potassiummolecular biophysicsnorepinephrine transporterserotonin transporterstructural biology

Identifiers

PMID34061030
PMCPMC8192120
OpenAlexW3165498665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.