Evidence map›Paper›PMID 34060904›Full record

ArticleJournal of bacteriology2021

PsaF Is a Membrane-Localized pH Sensor That Regulates

Joshua D Quinn, Eric H Weening, Virginia L Miller

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Co-component signal transduction systems: Fast-evolving virulence regulation cassettes discovered in enteric bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  5. DissectingJournal of bacteriology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joshua D QuinnDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
Eric H WeeningDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
Virginia L MillerDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
University of North Carolina at Chapel Hill · US

Funding

Yessinia autotransporters (Yaps): Structure, function, and host responseU54AI057157 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GOLDMAN, WILLIAM E · 2003 to 2013
$91.4M
Dissecting Bubonic PlagueR01AI119032 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MILLER, VIRGINIA L · 2015 to 2019
$1.9M
NIAID NIH HHS R01 AI119032NIAID NIH HHS U54 AI057157
6 · The paper itself

Abstract

The Yersinia pestis pH 6 antigen (PsaA) forms fimbria-like structures and is required for full virulence during bubonic plague. High temperature and low pH regulate PsaA production, and while recent work has uncovered the molecular aspects of temperature control, the mechanisms underlying this unusual regulation by pH are poorly understood. Using defined growth conditions, we recently showed that high levels of PsaE and PsaF (two regulatory proteins required for expression of

Indexed as

Gene Expression Regulation, BacterialAcidsAntigens, BacterialBacterial ProteinsCell MembraneHydrogen-Ion ConcentrationPhotosystem I Protein ComplexProtein TransportYersinia pestisAcidsAntigens, BacterialBacterial ProteinspH 6 antigen, YersiniaPhotosystem I Protein ComplexpsaF protein, bacteriaDegPpH 6 antigenpH sensingPsaAPsaEPsaFregulated intramembrane proteolysisTcpP/HToxR/STspYersinia pestisY. pestis

Identifiers

PMID34060904
PMCPMC8407435
OpenAlexW3165613305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.