Evidence map›Paper›PMID 34060873›Full record

ReviewBehavioral neuroscience2021

Defining an orbitofrontal compass: Functional and anatomical heterogeneity across anterior-posterior and medial-lateral axes.

Ines V Barreiros, Hironori Ishii, Mark E Walton, Marios C Panayi

Open access · greenAbstract readReview
In one paragraph

Review in Behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Dissociable Contributions of Basolateral Amygdala and Ventrolateral Orbitofrontal Cortex to Flexible Learning Under Uncertainty.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Compulsive drug-taking is associated with habenula-frontal cortex connectivity.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ines V BarreirosDepartment of Experimental Psychology, University of Oxford.ORCID 0000-0003-4610-9856
Hironori IshiiDepartment of Experimental Psychology, University of Oxford.
Mark E WaltonDepartment of Experimental Psychology, University of Oxford.
Marios C PanayiDepartment of Experimental Psychology, University of Oxford.ORCID 0000-0003-2635-5638
University of Oxford · GB

Funding

Biotechnology and Biological Sciences Research CouncilJapan Society for the Promotion of ScienceWellcome Trust 202831Wellcome Trust 202831/Z/16/Z
6 · The paper itself

Abstract

The orbitofrontal cortex (OFC) plays a critical role in the flexible control of behaviors and has been the focus of increasing research interest. However, there have been a number of controversies around the exact theoretical role of the OFC. One potential source of these issues is the comparison of evidence from different studies, particularly across species, which focus on different specific sub-regions within the OFC. Furthermore, there is emerging evidence that there may be functional diversity across the OFC which may account for these theoretical differences. Therefore, in this review we consider evidence supporting functional heterogeneity within the OFC and how it relates to underlying anatomical heterogeneity. We highlight the importance of anatomical and functional distinctions within the traditionally defined OFC subregions across the medial-lateral axis, which are often not differentiated for practical and historical reasons. We then consider emerging evidence of even finer-grained distinctions within these defined subregions along the anterior-posterior axis. These fine-grained anatomical considerations reveal a pattern of dissociable, but often complementary functions within the OFC. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Indexed as

Prefrontal Cortex

Identifiers

PMID34060873
PMCPMC7613671
OpenAlexW3130730282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.