ReviewBehavioral neuroscience2021
The orbitofrontal cortex in temporal cognition.
Review in Behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- The effects of rTMS over orbitofrontal cortex on cognitive functions in first-episode schizophrenia.Psychological medicine · 2026Trial
- Article
- Adaptive reward representations integrate expected uncertainty signals in orbitofrontal cortex.Science advances · 2025Article
- Neural representations of visual statistical learning based on temporal duration.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Effects of chronic stress on cognitive function - From neurobiology to intervention.Neurobiology of stress · 2024Review
- Educational disparities in brain health and dementia across Latin America and the United States.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Hippocampal and orbitofrontal neurons contribute to complementary aspects of associative structure.Nature communications · 2024Article
- A special role for anterior cingulate cortex, but not orbitofrontal cortex or basolateral amygdala, in choices involving information.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Accuracy of patient-reported spell duration: A comparative study.Epilepsy & behavior : E&B · 2024Article
- Time for Memories.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- The effect of emotion intensity on time perception: a study with transcranial random noise stimulation.Experimental brain research · 2023Article
- Dopamine-Dependent Ketamine Modulation of Glutamatergic Synaptic Plasticity in the Prelimbic Cortex of Adult Rats Exposed to Acute Stress.International journal of molecular sciences · 2023Article
- Possible rodent equivalent of the posterior cingulate cortex (area 23) interconnects with multimodal cortical and subcortical regions.Frontiers in neuroscience · 2023Article
- The neurophysiological Behavioral Perspective Model of consumer choice and its contribution to the intentional behaviorist research programme.Frontiers in human neuroscience · 2023Article
- Role of Orbitofrontal Cortex and Differential Effects of Acute and Chronic Stress on Motor Impulsivity Measured With 1-Choice Serial Reaction Time Test in Male Rats.The international journal of neuropsychopharmacology · 2022Article
- Neural population clocks: Encoding time in dynamic patterns of neural activity.Behavioral neuroscience · 2022Article
- Review
- When the inner clock fades: Interoceptive decline and consolidation of phase resetting in cortical rhythms by cardiac events underlie healthy lifespan aging.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
One of the most important factors in decision-making is estimating the value of available options. Subregions of the prefrontal cortex, including the orbitofrontal cortex (OFC), have been deemed essential for this process. Value computations require a complex integration across numerous dimensions, including, reward magnitude, effort, internal state, and time. The importance of the temporal dimension is well illustrated by temporal discounting tasks, in which subjects select between smaller-sooner versus larger-later rewards. The specific role of OFC in telling time and integrating temporal information into decision-making remains unclear. Based on the current literature, in this review we reevaluate current theories of OFC function, accounting for the influence of time. Incorporating temporal information into value estimation and decision-making requires distinct, yet interrelated, forms of temporal information including the ability to tell time, represent time, create temporal expectations, and the ability to use this information for optimal decision-making in a wide range of tasks, including temporal discounting and wagering. We use the term "temporal cognition" to refer to the integrated use of these different aspects of temporal information. We suggest that the OFC may be a critical site for the integration of reward magnitude and delay, and thus important for temporal cognition. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.