ArticleDiabetic medicine : a journal of the British Diabetic Association2021
Health-related quality of life in youth with type 1 diabetes: Associations with multiple comorbidities and mental health conditions.
Article in Diabetic medicine : a journal of the British Diabetic Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Disease control, psychiatric comorbidity, health-related quality of life, and experiences of care during transition to adult healthcare: a single-center prospective study.European journal of pediatrics · 2026Observational
- Article
- Long-Acting Growth Hormone Therapy in Pediatric Growth Hormone Deficiency: A Consensus Statement.The Journal of clinical endocrinology and metabolism · 2025Article
- Prevalence and Risk Factors for Bladder and Bowel Dysfunction in Children With Type 1 Diabetes.Pediatric diabetes · 2025Article
- Barriers to Type 1 Diabetes Adherence in Adolescents.Journal of clinical medicine · 2024Review
- Sociodemographic and Clinical Determinants on Health-Related Quality of Life in Emerging Andalusian Adults with Type 1 Diabetes: A Cross-Sectional Study.Journal of clinical medicine · 2023Article
- Prevalence of Bullying Victimization and Perpetration Among Youth with Chronic Health Conditions in the United States.Journal of child & adolescent trauma · 2023Article
- Health-related quality of life among adolescents with type 1 diabetes since the second wave of the COVID-19 pandemic in Germany.Family medicine and community health · 2023Article
- Proxy-report in individuals with intellectual disability: A scoping review.Journal of applied research in intellectual disabilities : JARID · 2022Article
- Psychosocial aspects of continuous subcutaneous insulin infusion in children with type 1 diabetes in Egypt; a limited resources country perspective.Diabetology & metabolic syndrome · 2022Article
- Comorbidities in Recent-Onset Adult Type 1 Diabetes: A Comparison of German Cohorts.Frontiers in endocrinology · 2022Observational
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
aimThis cross-sectional study examined the associations of comorbid conditions on health-related quality of life (HRQOL) in 601 youth with type 1 diabetes. We evaluated associations between number of comorbid conditions (0, 1, ≥2) and particular comorbid conditions and youth HRQOL by self-report and parent proxy-report. RESEARCH DESIGN AND
methodsYouth with type 1 diabetes, aged 5-18 years, and their parents completed the PedsQL 4.0 Generic Core Scales self-report and parent proxy-report, respectively; they also reported youths' comorbid medical and mental health conditions. Separate linear regression models tested the relationship between number of comorbid conditions and specific comorbid conditions with youth-reported and parent proxy-reported HRQOL.
resultsYouth with ≥2 comorbid conditions had significantly lower HRQOL by both self- and parent proxy-reports compared with youth with 0 or 1 comorbid condition (youth self-report: 0: 85 ± 12, 1: 85 ± 13, 2+: 78 ± 16, p = <0.0001; parent proxy-report: 0: 83 ± 12, 1: 81 ± 13, 2+: 74 ± 15, p = <0.0001). Amongst the comorbid conditions, only a mental health comorbidity was associated with lower HRQOL. For youth and parent proxy-reports, both the number of comorbidities (≥2) and the presence of a mental health comorbidity were significantly associated with lower HRQOL.
conclusionsHealth-related quality of life seems to be preserved in youth with type 1 diabetes unless confronted by multiple comorbidities as reported by youth and their parents. Our findings highlight the importance of tracking the presence of multiple comorbid conditions, possibly by reviewing problem and medication lists in the medical record, as well as screening for and addressing mental health conditions in routine diabetes care.
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