Evidence map›Paper›PMID 34060479›Full record

ReviewThe Journal of clinical investigation2021

The quagmire of race, genetic ancestry, and health disparities.

Giorgio Sirugo, Sarah A Tishkoff, Scott M Williams

Abstract readReview
In one paragraph

Review in The Journal of clinical investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Admixture mapping identifies complex trait associations with local ancestry in themedRxiv : the preprint server for health sciences · 2025
    Article
  6. Article
  7. A data model for population descriptors in genomic research.American journal of human genetics · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Online Database of Clinical Algorithms with Race and Ethnicity.medRxiv : the preprint server for health sciences · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giorgio SirugoInstitute of Systems Pharmacology and Translational Therapeutics.
Sarah A TishkoffDepartment of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Scott M WilliamsDepartments of Population and Quantitative Health Sciences, and Genetics and Genome Sciences, Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio, USA.

Funding

Genetic and molecular basis for variation in human skin pigmentationR01AR076241 · NIAMS · CHILDREN'S HOSP OF PHILADELPHIA · PI MARKS, MICHAEL S, OANCEA, ELENA · 2020 to 2024
$5.5M
Bioinformatics Strategies for Genome-Wide Association StudiesR01LM010098 · NLM · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H., WILLIAMS, SCOTT MATTHEW · 2009 to 2023
$5.1M
Undiagnosed diseases network clinical siteU01HG010219 · NHGRI · CHILDREN'S HOSP OF PHILADELPHIA · PI RADER, DANIEL JAMES, SULLIVAN, KATHLEEN E · 2018 to 2022
$3.0M
Integrative Genomic Analyses of Human Evolution and Adaptation in AfricaR35GM134957 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI TISHKOFF, SARAH ANNE · 2020 to 2024
$2.7M
Primaquine metabolism and treatment of P. vivax in MadagascarR01AI148469 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI WILLIAMS, SCOTT MATTHEW, ZIMMERMAN, PETER A. · 2020 to 2023
$2.6M
NHGRI NIH HHS U01 HG010219NIAID NIH HHS R01 AI148469NIAMS NIH HHS R01 AR076241NIGMS NIH HHS R35 GM134957NLM NIH HHS R01 LM010098
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Healthcare DisparitiesHumansRacial Groups

Identifiers

PMID34060479
PMCPMC8159696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.