Evidence map›Paper›PMID 34060415›Full record

ArticleBioengineered2021

Circular RNA 0102049 suppresses the progression of osteosarcoma through modulating miR-520g-3p/PLK2 axis.

Xianliao Zhang, Zhengbo Hu, Wenhu Li, Zhongxun Liu, Jie Li, Zhaozhen Wang, Vidmi Taolam Martin, Bing Yan, Bo Yu

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Osteosarcoma in a ceRNET perspective.Journal of biomedical science · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Xianliao ZhangDepartment of Orthopedics, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
Zhengbo HuDepartment of Orthopedics, Shaoguan First People's Hospital Affiliated to Southern Medical University, Shaoguan, China.
Wenhu LiDepartment of Orthopedics, Shaoguan First People's Hospital Affiliated to Southern Medical University, Shaoguan, China.
Zhongxun LiuDepartment of Orthopedics, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
Jie LiDepartment of Orthopedics, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
Zhaozhen WangDepartment of Orthopedics, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
Vidmi Taolam MartinDepartment of Orthopedics, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
Bing YanDepartment of Orthopedics, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
Bo YuDepartment of Orthopedics, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
Zhujiang Hospital · CNShaoguan University · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs) are a type of non-coding RNAs generated from back splicing to enhance or inhibit the progression of multiple human cancers including osteosarcoma (OS). Although circ_0102049 has been found to be highly expressed in OS cell lines, the role and specific mechanism of circ_0102049 in OS remains unclear. Here, we found that silence of circ_0102049 could significantly exacerbate the tumorigenesis of OS

Indexed as

AnimalsBone NeoplasmsCell Line, TumorCell ProliferationDisease ProgressionFemaleHumansMiceMice, Inbred BALB CMicroRNAsOsteosarcomaProtein Serine-Threonine KinasesRNA, CircularMicroRNAsPLK2 protein, humanProtein Serine-Threonine KinasesRNA, Circularcirc_0102049miR-520g-3pOsteosarcomaPLK2

Identifiers

PMID34060415
PMCPMC8806202
OpenAlexW3164349953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.