Evidence map›Paper›PMID 34060332›Full record

ArticlemBio2021

Nutrient Loading and Viral Memory Drive Accumulation of Restriction Modification Systems in Bloom-Forming Cyanobacteria.

Spiridon E Papoulis, Steven W Wilhelm, David Talmy, Erik R Zinser

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  9. Defense and anti-defense mechanisms of bacteria and bacteriophages.Journal of Zhejiang University. Science. B · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Spiridon E PapoulisDepartment of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
Steven W WilhelmDepartment of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
David TalmyDepartment of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
Erik R ZinserDepartment of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
University of Tennessee at Knoxville · US

Funding

The synergistic effects of climate and anthropogenic drivers on toxic cyanobacterial bloomsP01ES028939 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Gregory James Dick, David Joseph Kennedy · 2018 to 2026
$3.7M
NIEHS NIH HHS P01 ES028939
6 · The paper itself

Abstract

The mechanisms driving cyanobacterial harmful algal blooms (HABs) like those caused by Microcystis aeruginosa remain elusive, but improved defense against viral predation has been implicated for success in eutrophic environments. Our genus-level analyses of 139,023 genomes revealed that HAB-forming cyanobacteria carry vastly more restriction modification systems per genome (RMPG) than nearly all other prokaryotic genera, suggesting that viral defense is a cornerstone of their ecological success. In contrast, picocyanobacteria that numerically dominate nutrient-poor systems have the fewest RMPG within the phylum

Indexed as

Genome, BacterialBacteriophagesCyanobacteriaDNA Restriction-Modification EnzymesHarmful Algal BloomNutrientsWater QualityDNA Restriction-Modification EnzymesNutrientseutrophicationharmful algal bloomsMicrocystisviral defense

Identifiers

PMID34060332
PMCPMC8262939
OpenAlexW3164154153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.