Evidence map›Paper›PMID 34059762›Full record

ArticleScientific reports2021

Neutrophil to lymphocyte ratio and fibrinogen values in predicting patients with type B aortic dissection.

Shuangshuang Li, Jin Yang, Jian Dong, Renle Guo, Sheng Chang, Hongqiao Zhu, Zhaohui Li, Jian Zhou, Zaiping Jing

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Neutrophil/lymphocyte ratio as a predictor of mortality among aortic dissection patients in the emergency department.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Shuangshuang Li *Department of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, 200433, China.
Jin Yang *Department of Vascular Surgery, Suining Central Hospital, No. 127 Desheng West Road, Chuanshan District, Suining, 629000, Sichuan Province, China.
Jian Dong *Department of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, 200433, China.
Renle GuoDepartment of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, 200433, China.
Sheng ChangDepartment of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, 200433, China.
Hongqiao ZhuDepartment of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, 200433, China.
Zhaohui LiDepartment of Vascular of Surgery, The First People's Hostpital of Yibin, Yibin, 644000, China. 1187510153@qq.com.
Jian ZhouDepartment of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, 200433, China. zhoujian1-2@163.com.
Zaiping JingDepartment of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, 200433, China. xueguanky@163.com.
Second Military Medical University · CNChanghai Hospital · CNSecond People’s Hospital of Yibin · CNSuizhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to detect the diagnosis value of neutrophil lymphocyte ratio (NLR) and fibrinogen (FIB) in type B aortic dissection (TBAD) patients. This retrospective observation study consisted patients with TBAD, aortic aneurysm and physical examination between January 1, 2016 and December 31, 2019. Demographic and clinical information after the first admission were collected. Multivariate logistic regression analysis was performed to explore the correlational relationship between NLR, FIB and TBAD. Receiver Operating Characteristic Curve (ROC) was performed to evaluate the diagnostic implication of NLR and FIB in TBAD patients. Six hundred and six patients who were first diagnosed with TBAD were included. Control groups were 202 aortic aneurysm and 140 physical examination subjects. The level of NLR and FIB in aortic dissection patients was significantly higher than aortic aneurysm patients and healthy group (P < 0.001). According to the results of multivariate logistic regression analysis, NLR and FIB were independent risk factors of aortic dissection, and the odds ratio (OR) and 95% confidence interval (CI) value of NLR and FIB were 1.499 (1.126-1.738) and 1.914 (1.475-2.485), respectively. The area under the curve (AUC) was 0.836 of NLR and 0.756 of FIB. NLR and FIB showed high specificity, 89% and 83% respectively. This is the first study provided information on the diagnosis performance of NLR and FIB in TBAD patients. NLR and FIB showed high specificity, which may be a valuable tool for the diagnosis of TBAD.

Indexed as

AgedAortic DissectionCase-Control StudiesFemaleFibrinogenHumansLymphocytesMaleMiddle AgedNeutrophilsPrognosisRisk FactorsFibrinogen

Identifiers

PMID34059762
PMCPMC8166888
OpenAlexW3123886265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.