ArticleScientific reports2021
Changes in each retinal layer and ellipsoid zone recovery after full-thickness macular hole surgery.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Long-Term Structural and Functional Restoration of the Retina After Inverted Internal Limiting Membrane Flap Surgery for Idiopathic Full-Thickness Macular Holes.Diagnostics (Basel, Switzerland) · 2026Article
- Polarimetric entropy mapping of retinal pigment epithelium in full-thickness macular hole by polarization-sensitive OCT.BMC ophthalmology · 2026Article
- High-altitude retinopathy with isolated ellipsoid zone loss: a case report.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- The outer nuclear layer changes in full-thickness macular holes according to the restoration of the outer retinal layer postoperatively.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Novel TA-IVIZ Patch and BSS Tamponade for Macular Hole Repair: A Pilot Study.Translational vision science & technology · 2025Article
- Minimal Gas Vitrectomy and As-Needed Positioning Duration for Idiopathic Macular Holes.Ophthalmology and therapy · 2025Article
- The Ellipsoid Zone Is a Structural Biomarker for Visual Outcomes in Diabetic Macular Edema and Macular Hole Management.Vision (Basel, Switzerland) · 2025Article
- Microstructural and hemodynamic changes in the fundus after pars plana vitrectomy for different vitreoretinal diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Review
- Outcomes of epiretinal proliferation embedding technique in the surgery for full-thickness macular hole.Scientific reports · 2024Article
- Accuracy of generative deep learning model for macular anatomy prediction from optical coherence tomography images in macular hole surgery.Scientific reports · 2024Article
- Pathoanatomical aspects of macular hole closure: Emerging concepts.Indian journal of ophthalmology · 2024Article
- Internal limiting membrane peeling combined with mouse nerve growth factor injection for idiopathic macular hole.BMC ophthalmology · 2023Article
- Indistinct retinal outer layers in the walls of the idiopathic full-thickness macular hole - A potential predictive biomarker for surgical outcomes.Indian journal of ophthalmology · 2022Observational
- Visual improvement and regeneration of retinal layers in eyes with small, medium, and large idiopathic full-thickness macular holes treated with the inverted internal limiting membrane flap technique over a period of 12 months.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- Postoperative microstructural re-modelling and functional outcomes in idiopathic full thickness macular hole.Indian journal of ophthalmology · 2022Article
- Ellipsoid Zone and External Limiting Membrane-Related Parameters on Spectral Domain-Optical Coherence Tomography and Their Relationships With Visual Prognosis After Successful Macular Hole Surgery.Frontiers in medicine · 2021Article
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5 authors.
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Abstract
To analyze the changes in each retinal layer and the recovery of the ellipsoid zone (EZ) after full-thickness macular hole (FTMH) surgery. Patients who underwent surgery for FTMH were included. Spectral-domain optical coherence tomography (SD-OCT) was performed preoperatively and postoperatively at 1, 3, 6, 9, and 12 months. A total of 32 eyes were enrolled. Ganglion cell layer, inner plexiform layer, and inner nuclear layer showed significant reductions over time after surgery (P = 0.020, P = 0.001, and P = 0.001, respectively), but were significantly thicker than those of fellow eyes at 12 months postoperatively. The average recovery duration of the external limiting membrane (ELM), outer nuclear layer (ONL), and EZ was 1.5, 2.1, and 6.1 months, respectively. Baseline best-corrected visual acuity (BCVA) (P = 0.003), minimum linear diameter (MLD) (P = 0.025), recovery of EZ (P = 0.008), and IRL thickness (P < 0.001) were significant factors associated with changes in the BCVA. Additionally, axial length (P < 0.001), MLD (P = 0.020), and IRL thickness (P = 0.001) showed significant results associated with EZ recovery. The IRL gradually became thinner after FTMH surgery but was still thicker than that of the fellow eye at 12 months postoperatively. The recovery of ELM and ONL may be a prerequisite for the EZ recovery. The BCVA change was affected by baseline BCVA, MLD, recovery of EZ, and IRL thickness. Additionally, axial length, MLD, and IRL thickness were significantly associated with EZ recovery.
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