ArticleSurgery2021
The impact of obesity and severe obesity on postoperative outcomes after pancreatoduodenectomy.
Article in Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Mortality and complications in patients with obesity after open, robotic or laparoscopic pancreaticoduodenectomy: A systematic review and meta-analysis.International journal of obesity (2005) · 2025Pooled it
- The optimal choice for patients underwent minimally invasive pancreaticoduodenectomy: a systematic review and meta-analysis including patient subgroups.Surgical endoscopy · 2024Pooled it
- Conversion to open surgery during robotic pancreatoduodenectomy in surgical high-risk groups: patterns, risk factors, and outcomes in elderly and/or obese patients.Surgical endoscopy · 2026Observational
- The Impact of Obesity on Intraoperative, Oncological, and Postoperative Endpoints in Robotic Pancreaticoduodenectomy.World journal of surgery · 2026Article
- ASO Author Reflections: Waist-to-Height Ratio Predicts Pancreatic Fistula after Pancreatoduodenectomy.Annals of surgical oncology · 2026Article
- Waist-to-Height Ratio as a Predictor Complementary to BMI for Postoperative Pancreatic Fistula After Pancreatoduodenectomy for Periampullary Tumors.Annals of surgical oncology · 2026Article
- Associations between obesity and lymph node metastasis and early recurrence in pancreatic head cancer: A single-center retrospective cohort study.Surgery in practice and science · 2026Article
- Graded and threshold effects of body mass index on perioperative outcomes after pancreaticoduodenectomy: a meta-analysis incorporating an institutional cohort.Frontiers in surgery · 2026Article
- Skeletal muscle mass associates with pancreaticoduodenectomy operative time in a sex-dependent manner.BMC cancer · 2025Article
- Precision Anatomy Matters: A Standardized Approach to Mesojejunal Dissection During Pancreaticoduodenectomy.Annals of surgical oncology · 2025Article
- Validation of the Updated Alternate Fistula Risk Score for Prediction of Postoperative Pancreatic Fistula After Pancreatoduodenectomy.JGH open : an open access journal of gastroenterology and hepatology · 2024Article
- Thick mesopancreas is a novel predictor of surgical outcomes of patients who undergo pancreaticoduodenectomy.Langenbeck's archives of surgery · 2024Article
- Article
- A Single-Center Retrospective Study of Selected Clinical Parameters and Intraoperative Fluid Management of Patients Undergoing Pancreatoduodenectomy.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe impact of obesity on postoperative outcomes after pancreatoduodenectomy remains insufficiently studied.
methodsAll pancreatoduodenectomy patients were abstracted from the 2014 to 2018 American College of Surgeons National Surgical Quality Improvement Program data sets and were stratified into the following 3 body mass index categories: non-obese (body mass index 18.5-29.9), class 1/2 obesity (body mass index 30-39.9), and class 3 severe obesity (body mass index ≥ 40). Analyses tested associations between patient factors and four 30-day postoperative outcomes: mortality, composite morbidity, delayed gastric emptying, and postoperative pancreatic fistula. Multivariable logistic regression models tested independent associations between patient factors and these 4 outcome measures.
resultsA total of 16,823 patients were included in the study: 12,234 (72.7%) non-obese, 4,030 (24%) obese, and 559 (3.3%) with severe obesity. Bivariable analyses demonstrated significant associations between obesity, severe obesity, and greater proportions of numerous preoperative comorbidities as well as a greater likelihood of postoperative complications, including postoperative pancreatic fistula, delayed gastric emptying, composite morbidity, and mortality (all P ≤ .001). After adjusting for significant covariates, obesity was independently associated with postoperative pancreatic fistula (odds ratio 1.49, 95% confidence interval: 1.33-1.67, P < .001), delayed gastric emptying (odds ratio 1.16, 95% confidence interval: 1.05-1.28, P = .004), composite morbidity (odds ratio 1.28, 95% confidence interval: 1.18-1.38, P < .001), and mortality (odds ratio 1.79, 95% confidence interval: 1.36-2.36, P < .001).
conclusionObesity and severe obesity are significantly associated with worse short-term outcomes after pancreatoduodenectomy. Preoperative considerations, such as weight management strategies during individualized treatment planning, could improve outcomes in this population.
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Registered trials
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