ArticleCardio-oncology (London, England)2021
Metastatic colorectal carcinoma to the right atrium: a case report and review of the literature.
Article in Cardio-oncology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Cardiac metastases from colorectal cancer: a comprehensive systematic review of clinical presentation, cardiac involvement, and outcomes.Clinical & experimental metastasis · 2026Pooled it
- Metastatic Soft Tissue Sarcoma With Cardiac Involvement: A Case Study on the Role of Multimodal Imaging in Diagnosis and Management.Clinical case reports · 2026Article
- Complete Heart Block and Massive Pericardial Effusion as the Presenting Manifestations of Metastatic Colorectal Adenocarcinoma.JACC. Case reports · 2026Article
- Right Ventricular Metastasis From Rectal Cancer Recurrence.JACC. Case reports · 2026Article
- Novel use of stereotactic ablative radiotherapy for refractory ventricular tachycardia with cardiac metastasis of primary renal cell carcinoma: a case report.Cardio-oncology (London, England) · 2025Article
- Unexpected journey: a colon adenocarcinoma metastatic to the heart.Journal of surgical case reports · 2025Article
- Cardiac Septal Metastasis From Poorly Differentiated Colorectal Adenocarcinoma: A Rare Case Illustrating the Role of Multimodal Imaging and Multidisciplinary Management.Case reports in cardiology · 2025Article
- Cardiac Tumors: Review.Brazilian journal of cardiovascular surgery · 2024Review
- Complex decision making in a patient with lung cancer with incidentally found fast-growing atrial mass.Cardio-oncology (London, England) · 2024Article
- Metastasis of colorectal adenocarcinoma to the right ventricle in a young man: a case report.The Pan African medical journal · 2023Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiac metastasis due to colon cancer is extraordinarily uncommon. Given the rarity of diagnosis, there is paucity of evidence and hence, no established guidelines for evaluation or clinical management strategy. CLINICAL PRESENTATION: We present the case of a 59 year old male with a previously treated colonic carcinoma who presented with new onset exertional dyspnea. He was noted to be having a right atrial mass on an echocardiogram performed at his cardiologist's office. Further workup with CT angiogram of the chest confirmed a right atrial mass measuring 4.0 cm. Serum CEA was normal. Biopsies of the right atrial mass demonstrated metastatic moderately differentiated colonic adenocarcinoma. Mismatch repair protein expression analysis by immunohistochemistry showed no loss of MLH1, MSH2, MSH6 or PMS2 expression. Next generation sequencing for RAS and BRAF mutations was negative. Patient received treatment with FOLFIRINOX/ bevacizumab with noted reduction in size of mass.
conclusionTo the best of our knowledge, this is the first report of next generation sequencing results available on a biopsy of metastatic colorectal cancer to the heart with the largest literature review of 31 reported cases of metastatic colorectal cancer to the heart. It will help direct clinical management and also adds evidence to the potential efficacy of treatment of this rare aggressive disease with chemotherapy in combination with VEGF inhibitors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.