ArticleAlzheimer's research & therapy2021
Longitudinal change in hippocampal and dorsal anterior insulae functional connectivity in subjective cognitive decline.
Article in Alzheimer's research & therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Hyperbolic Graph Embedding of MEG Brain Networks to Study Brain Alterations in Individuals With Subjective Cognitive Decline.IEEE journal of biomedical and health informatics · 2024Article
- Association between Subjective Cognitive Complaints and Sleep Disturbance among Community-Dwelling Elderly Individuals in Japan.Healthcare (Basel, Switzerland) · 2024Article
- An exploration of distinguishing subjective cognitive decline and mild cognitive impairment based on resting-state prefrontal functional connectivity assessed by functional near-infrared spectroscopy.Frontiers in aging neuroscience · 2024Article
- Dysfunctions of multiscale dynamic brain functional networks in subjective cognitive decline.Brain communications · 2024Article
- Distinct functional subnetworks of cognitive domains in older adults with minor cognitive deficits.Brain communications · 2024Article
- Hyperbolic graph embedding of MEG brain networks to study brain alterations in individuals with subjective cognitive decline.bioRxiv : the preprint server for biology · 2023Article
- Mapping human brain charts cross-sectionally and longitudinally.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- R4Alz-Revised: A Tool Able to Strongly Discriminate 'Subjective Cognitive Decline' from Healthy Cognition and 'Minor Neurocognitive Disorder'.Diagnostics (Basel, Switzerland) · 2023Article
- Recent contributions to the field of subjective cognitive decline in aging: A literature review.Alzheimer's & dementia (Amsterdam, Netherlands)Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSubjective cognitive decline, perceived worsening of cognitive ability without apparent performance issues on clinical assessment, may be an important precursor to dementia. While previous cross-sectional research has demonstrated aberrant brain functional connectivity in subjective cognitive decline, longitudinal evaluation remains limited.
methodsHere, we examined trajectories of functional connectivity over three measurement occasions ~18 months apart, using voxelwise latent growth models in cognitively unimpaired older adults with varying self-report of subjective cognitive decline (N = 69).
resultsWe found that individuals who reported a greater degree of subjective cognitive decline showed a larger subsequent decrease in connectivity between components of the default mode network and increase in connectivity between salience and default mode network components. The change in functional connectivity was observed in the absence of change in cognitive performance.
conclusionThe results indicate that functional brain changes may underly the experience of cognitive decline before deterioration reaches a level detected by formal cognitive assessment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.