ArticleReproductive biology and endocrinology : RB&E2021
Ectopic pregnancy: a single-center experience over ten years.
Article in Reproductive biology and endocrinology : RB&E, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 71 citations in OpenAlex.
- Increased Endometrial CD38 and CD138 Positivity in Women with Ectopic Pregnancy History: A Retrospective Study.Reproductive sciences (Thousand Oaks, Calif.) · 2026Article
- Ovarian pregnancy: clinical characteristics, diagnostic challenges, and sonographic features-a multicenter case series with narrative literature overview.Archives of gynecology and obstetrics · 2026Review
- The Predictive Value of Systemic Inflammatory Markers from Failed Single-Dose Methotrexate Therapy in Tubal Ectopic Pregnancy: A Retrospective Single-Center Study.Journal of inflammation research · 2026Article
- Ectopic Pregnancy Mortality Trends in BRICS: Age-Period-Cohort Analysis of Global Burden Disease 2021 Data and 2030 Forecast.Clinical epidemiology · 2026Article
- Clinical Profile, Surgical Treatment, and Outcomes of Ectopic Pregnancy in a Tertiary Training Hospital in the Philippines.Acta medica Philippina · 2026Article
- Ovarian Ectopic Pregnancy, an Unusual Diagnosis-Two Cases With Two Distinct Treatment Approaches.Clinical case reports · 2025Article
- Ovarian pregnancy following fresh embryo transfer: A case report and literature review.Case reports in women's health · 2025Article
- Distinguishing tubal rupture from tubal abortion in ectopic pregnancies after methotrexate treatment: a retrospective cohort study.Archives of gynecology and obstetrics · 2025Article
- Contrast enhanced ultrasound - a useful method for diagnosing tubal ectopic pregnancy with low level β-HCG.The ultrasound journal · 2025Article
- Misdiagnosis of a Term Abdominal Ectopic Pregnancy: A Case Report.JNMA; journal of the Nepal Medical Association · 2025Article
- Association of endometrial preparation protocols and embryonic development stages with ectopic pregnancy in freeze-thaw cycles.Journal of assisted reproduction and genetics · 2025Article
- Analysis of ectopic pregnancies requiring life-saving urgent surgery.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- Article
- Effect of Single and Multiple Methotrexate Doses Treatment on Ovarian Reserve in Ectopic Pregnancy Women: A Prospective Cohort Study.Journal of obstetrics and gynaecology of India · 2025Article
- Ultrasound Features and Outcomes of Assisted Reproductive Technology-Conceived Heterotopic Pregnancies.International journal of women's health · 2025Article
- An individualized risk prediction tool for ectopic pregnancy within the first 10 weeks of gestation based on machine learning algorithms.Frontiers in medicine · 2025Article
- Hormonal and electrolyte predictors for methotrexate versus surgery in ectopic pregnancy.PloS one · 2025Article
- Development and Validation of a Machine Learning-Based Clinical Model for Predicting Rupture in Ectopic Pregnancy: A Web-Based Nomogram Approach.Journal of multidisciplinary healthcare · 2025Article
- Primary rectal ectopic pregnancy: a rare case report and literature review.Frontiers in medicine · 2025Article
- The relationship between serum levels of epidermal growth factor and β-human chorionic gonadotropin and the type and prognosis of ectopic pregnancy.Archives of gynecology and obstetrics · 2024Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to investigate characteristics associated with ectopic pregnancy (EP) that could be utilized for predicting morbidity or mortality.
methodsThis was a retrospective analysis of pregnancy-related records from a tertiary center over a period of ten years. Data on age, gravidity, parity, EP risk, amenorrhea duration, abdominal pain presence and location, β-human chorionic gonadotropin (β-HCG) level, ultrasound findings, therapeutic intervention, exact EP implantation site and length of hospital stay (LOS) were obtained from the database. The LOS was used as a proxy for morbidity and was tested for an association with all variables. All statistical analyses were conducted with Stata® (ver. 16.1, Texas, USA).
resultsThe incidence of EP in a cohort of 30,247 pregnancies over a ten-year period was 1.05%. Patients presented with lower abdominal pain in 87.9% of cases, and the likelihood of experiencing pain was tenfold higher if fluid was detectable in the pouch of Douglas. Only 5.1% of patients had a detectable embryonic heartbeat, and 18.15% had one or more risk factors for EP. While most EPs were tubal, 2% were ovarian. The LOS was 1.9 days, and laparoscopic intervention was the main management procedure. The cohort included one genetically proven dizygotic heterotopic pregnancy (incidence, 3.3 × 10
conclusionEP is a relatively common condition affecting approximately 1% of all pregnancies. β-HCG correlates with EP-related morbidity, but the overall morbidity rate of EP is low regardless of the implantation site. Laparoscopic surgery is an effective therapeutic procedure that is safe for managing EP, even in cases of heterotopic pregnancy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.