ReviewNeuroImage2021
GABA and glutamate in the preterm neonatal brain: In-vivo measurement by magnetic resonance spectroscopy.
Review in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 36 citations in OpenAlex.
- Revolutionizing Pediatric Neurophysiology With Magnetoencephalography.Psychophysiology · 2026Review
- Neonatal pain experience and pain sensitivity trajectories in preterm infants: A longitudinal study of flexion withdrawal reflex thresholds over the first two years of age.The journal of pain · 2025Article
- Development of brain metastable dynamics during the equivalent of the third gestational trimester.Developmental cognitive neuroscience · 2025Review
- The Role of Proton Magnetic Resonance Spectroscopy in Neonatal and Fetal Brain Research.Journal of magnetic resonance imaging : JMRI · 2025Review
- Early medical risks to language development in extremely preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Gut microbial GABA imbalance emerges as a metabolic signature in mild autism spectrum disorder linked to overrepresented Escherichia.Cell reports. Medicine · 2025Article
- A comprehensive review of GABA in autism spectrum disorders: associations, mechanisms, and therapeutic implications.Frontiers in psychiatry · 2025Review
- Gestational Duration and Postnatal Age-Related Changes in Aperiodic and Periodic Parameters in Neonatal and Toddler Electroencephalogram (EEG).Human brain mapping · 2025Article
- CEST MRI detects antiretroviral drug toxicities in the developing mouse brain.Frontiers in pharmacology · 2025Article
- Sleep as a driver of pre- and postnatal brain development.Pediatric research · 2024Review
- Multi-omics insights into beagle dog fed with a sucking-rewarded automatic feeding device.Frontiers in pediatrics · 2024Article
- Physiologically Based Pharmacokinetics Modeling in the Neonatal Population-Current Advances, Challenges, and Opportunities.Pharmaceutics · 2023Review
- Impact of bronchopulmonary dysplasia on brain GABA concentrations in preterm infants: Prospective cohort study.Early human development · 2023Article
- Severity of prematurity and age impact early postnatal development of GABA and glutamate systems.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Glutamate alterations in the premature infant brain during different gestational ages with glutamate chemical exchange saturation transfer imaging: a pilot study.European radiology · 2023Article
- Developmental and epileptic encephalopathy 89: A novel bi-allelic variant, molecular dynamics simulation, and a comprehensive clinical and molecular profile.Epilepsia open · 2023Article
- A perspective on molecular signalling dysfunction, its clinical relevance and therapeutics in autism spectrum disorder.Experimental brain research · 2022Review
- Human Breast Milk: The Key Role in the Maturation of Immune, Gastrointestinal and Central Nervous Systems: A Narrative Review.Diagnostics (Basel, Switzerland) · 2022Review
- Quantifying GABA in Addiction: A Review of Proton Magnetic Resonance Spectroscopy Studies.Brain sciences · 2022Review
- Unilateral Transient Enhanced SEP during Integrated Multiparameter Neurophysiological Monitoring in a Newborn with Symptomatic Seizure.Pediatric reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Cognitive and behavioral disabilities in preterm infants, even without obvious brain injury on conventional neuroimaging, underscores a critical need to identify the subtle underlying microstructural and biochemical derangements. The gamma-aminobutyric acid (GABA) and glutamatergic neurotransmitter systems undergo rapid maturation during the crucial late gestation and early postnatal life, and are at-risk of disruption after preterm birth. Animal and human autopsy studies provide the bulk of current understanding since non-invasive specialized proton magnetic resonance spectroscopy (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.