Evidence map›Paper›PMID 34058256›Full record

Trial reportInternational journal of radiation oncology, biology, physics2021

The Influence of Patient-Provider Language Concordance in Cancer Care: Results of the Hispanic Outcomes by Language Approach (HOLA) Randomized Trial.

Daniel M Seible, Souma Kundu, Alexa Azuara, Daniel R Cherry, Steven Arias, Vinit V Nalawade, Jonathan Cruz, Rolando Arreola, Maria Elena Martinez, Jesse N Nodora and 2 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of radiation oncology, biology, physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07787806 (A Randomized Controlled, Type 1 Hybrid Effectiveness-implementation Trial Study to Compare the Effectiveness of a Patient-Reported Outcomes), which is not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07787806 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Randomized Controlled, Type 1 Hybrid Effectiveness-implementation Trial Study to Compare the Effectiveness of a Patient-Reported Outcomes (PRO)-Driven Culturally Grounded Supportive Care Navigation in Reducing Healthcare Disparities Among Hispanic/Latinx Patients Receiving Anticancer Therapies

TypeinterventionalSponsorUniversity of California, IrvineRan2026 to 2028Enrolled72ConditionsCancerArmsPatient-Reported Outcomes (PRO)-driven supportive care navigation
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The patient perspective on diversity-sensitive care: a systematic review.International journal for equity in health · 2024
    Pooled it
  4. Article
  5. Article
  6. Preguntas Sobre Cáncer (Questions About Cancer): Analysis of Spanish Inquiries to the National Cancer Institute's Cancer Information Service.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
  7. Article
  8. When Language is Care.Journal of immigrant and minority health · 2026
    Article
  9. Article
  10. Factors influencing care for patients with gynecologic malignancies from culturally and linguistically diverse backgrounds: a questionnaire study (iCALD-2).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. "Interpreters don't tell you everything": experiences with medical interpretation among Latino cancer patients and caregivers with limited English proficiency.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  18. Article
  19. The Flipped Classroom Approach: A Feasible Way to Teach the Physical Exam in Spanish.MedEdPORTAL : the journal of teaching and learning resources · 2025
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Daniel M SeibleDepartment of Radiation Medicine and Applied Sciences, University of California, San Diego, California.
Souma KunduSchool of Medicine, University of California, San Diego, California.
Alexa AzuaraDepartment of Radiation Medicine and Applied Sciences, University of California, San Diego, California.
Daniel R CherrySchool of Medicine, University of California, San Diego, California.
Steven AriasSchool of Medicine, University of California, San Diego, California.
Vinit V NalawadeDepartment of Radiation Medicine and Applied Sciences, University of California, San Diego, California.
Jonathan CruzSchool of Medicine, University of California, San Diego, California.
Rolando ArreolaDepartment of Radiation Medicine and Applied Sciences, University of California, San Diego, California.
Maria Elena MartinezDepartment of Family and Preventive Medicine, University of California, San Diego, California.
Jesse N NodoraDepartment of Family Medicine and Public Health, University of California, San Diego, California.
Douglas A RahnDepartment of Radiation Medicine and Applied Sciences, University of California, San Diego, California.
James D MurphyDepartment of Radiation Medicine and Applied Sciences, University of California, San Diego, California. Electronic address: j2murphy@ucsd.edu.
University of California San Diego · US

Funding

Research Education CoreU54CA132384 · NCI · SAN DIEGO STATE UNIVERSITY · PI CRIPPS, RICHARD MATTHEW, CROWE, SHEILA E. · 2008 to 2022
$20.7M
Research Education CoreU54CA132379 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ARREDONDO, ELVA M, CROWE, SHEILA E. · 2008 to 2021
$16.1M
UC San Diego Clinical and Translational Research InstituteTL1TR001443 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2015 to 2019
$3.4M
NCATS NIH HHS TL1 TR001443NCI NIH HHS U54 CA132379NCI NIH HHS U54 CA132384
6 · The paper itself

Abstract

purposeDelivering linguistically competent care is critical to serving patients who have limited English proficiency (LEP) and represents a key national strategy to help reduce health disparities. Current acceptable standards of communication with patients who have LEP include providers communicating through professional interpretive services or bilingual providers speaking the patients' preferred language directly. This randomized clinical trial tests the effect of patient-provider language concordance on patient satisfaction. METHODS AND MATERIALS: Eighty-three adult Spanish-speaking patients with cancer were randomly assigned to receive care from either (1) 1 of 2 bilingual physicians speaking to the patient directly in Spanish or (2) the same physicians speaking English and using a professional interpreter service. Validated questionnaires were administered to assess patient-reported satisfaction with both provider communication and overall care. Transcripts of initial consultations were analyzed for content variations.

resultsCompared with patients receiving care through professional interpretive services, patients cared for in direct Spanish reported significantly improved general satisfaction, technical quality of care (mean composite score [MCS], 4.41 vs 4.06; P = .005), care team interpersonal manner (MCS, 4.37 vs 3.88; P = .004), communication (MCS, 4.50 vs 4.25; P = .018), and time spent with patient,(MCS, 4.30 vs 3.92; P = .028). Specific to physician communication, patients rated direct-Spanish care more highly in perceived opportunity to disclose concerns (MCS 4.91 vs 4.62; P = .001), physician empathy (MCS, 4.94 vs 4.59; P <.001), confidence in physician abilities (MCS, 4.84 vs 4.51; P = .001), and general satisfaction with their physician (MCS, 4.88 vs 4.59; P <.001). Analyzing the content of consultation encounters revealed differences between study arms, with the direct-Spanish arm having more physician speech related to patient history verification (mean number of utterances, 13 vs 9; P = .01) and partnering activities (mean utterances, 16 vs 5; P <.001). Additionally, patients in the direct-Spanish arm were more likely to initiate unprompted speech (mean utterances, 11 vs 3; P <.001) and asked their providers more questions (mean utterances, 11 vs 4; P = .007).

conclusionsThis study shows improved patient-reported satisfaction among patients with cancer who had LEP and were cared for in direct Spanish compared with interpreter-based communication. Further research into interventions to mitigate the patient-provider language barrier is necessary to optimize care for this population.

Indexed as

LanguageNeoplasmsAdultCommunication BarriersHispanic or LatinoHumansPatient SatisfactionPhysician-Patient Relations

Identifiers

PMID34058256
PMCPMC9137326
OpenAlexW3094569378

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.