Evidence map›Paper›PMID 34058012›Full record

ArticleJournal of the American Geriatrics Society2021

COVID-19 disease trajectories among nursing home residents.

Jennifer L Carnahan, Kristi M Lieb, Lauren Albert, Kamal Wagle, Ellen Kaehr, Kathleen T Unroe

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Role of senescence in the chronic health consequences of COVID-19.Translational research : the journal of laboratory and clinical medicine · 2022
    Review
  7. Article
  8. COVID-19 disease trajectories among nursing home residents.Journal of the American Geriatrics Society · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jennifer L CarnahanIndiana University School of Medicine, Department of Medicine, Division of General Internal Medicine and Geriatrics, Indianapolis, Indiana, USA.ORCID 0000-0001-9964-4735
Kristi M LiebIndiana University School of Medicine, Department of Medicine, Division of General Internal Medicine and Geriatrics, Indianapolis, Indiana, USA.
Lauren AlbertIndiana University School of Medicine, Department of Medicine, Division of General Internal Medicine and Geriatrics, Indianapolis, Indiana, USA.
Kamal WagleIndiana University School of Medicine, Department of Medicine, Division of General Internal Medicine and Geriatrics, Indianapolis, Indiana, USA.
Ellen KaehrIndiana University School of Medicine, Department of Medicine, Division of General Internal Medicine and Geriatrics, Indianapolis, Indiana, USA.
Kathleen T UnroeIndiana University School of Medicine, Department of Medicine, Division of General Internal Medicine and Geriatrics, Indianapolis, Indiana, USA.
Regenstrief Institute · USRichard L. Roudebush VA Medical Center · USIndiana University Health · USIndiana University School of Medicine

Funding

The Coming Home After Rehabilitation and Transition from a Skilled nursing facility with Dementia Study (The CHARTS-D Study)K23AG062797 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI CARNAHAN, JENNIFER LYNN · 2020 to 2024
$902k
Centers for Medicare and Medicaid Services 1E1CMS331488NIA NIH HHS K23 AG062797NIA NIH HHS K23AG062797
6 · The paper itself

Abstract

introductionOlder adults are at greater risk of both infection with and mortality from COVID-19. Many U.S. nursing homes have been devastated by the COVID-19 pandemic, yet little has been described regarding the typical disease course in this population. The objective of this study is to describe and identify patterns in the disease course of nursing home residents infected with COVID-19. SETTING AND

methodsThis is a case series of 74 residents with COVID-19 infection in a nursing home in central Indiana between March 28 and June 17, 2020. Data were extracted from the electronic medical record and from nursing home medical director tracking notes from the time of the index infection through August 31, 2020. The clinical authorship team reviewed the data to identify patterns in the disease course of the residents.

resultsThe most common symptoms were fever, hypoxia, anorexia, and fatigue/malaise. The duration of symptoms was extended, with an average of over 3 weeks. Of those infected 25 died; 23 of the deaths were considered related to COVID-19 infection. A subset of residents with COVID-19 infection experienced a rapidly progressive, fatal course. DISCUSSION/

conclusionsNursing home residents infected with COVID-19 from the facility we studied experienced a prolonged disease course regardless of the severity of their symptoms, with implications for the resources needed to care for and support of these residents during active infection and post-disease. Future studies should combine data from nursing home residents across the country to identify the risk factors for disease trajectories identified in this case series.

Indexed as

SARS-CoV-2AgedAged, 80 and overCOVID-19FemaleHomes for the AgedHumansIndianaMaleNursing HomesRisk FactorsSeverity of Illness IndexCOVID-19disease trajectorylong-term carenursing home

Identifiers

PMID34058012
PMCPMC8242389
OpenAlexW3165828633

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.