Evidence map›Paper›PMID 34057015›Full record

ArticleBioengineered2021

Interleukin IL-5 alleviates sepsis-induced acute lung injury by regulating the immune response in rats.

Beichun Wei, Yu Chen, Wangmei Zhou, Xu Li, Lei Shi, Shengwu Liao

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Traumatic inflammatory response: pathophysiological role and clinical value of cytokines.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Beichun WeiDepartment of Emergency, Nanfang Hospital, Southern Medical University, Guangdong, China.
Yu ChenDepartment of Anesthesiology, The Sixth Medical Center of Chinese PLA General Hospital, Beijing, China.
Wangmei ZhouDepartment of Emergency, Nanfang Hospital, Southern Medical University, Guangdong, China.
Xu LiDepartment of Emergency, Nanfang Hospital, Southern Medical University, Guangdong, China.
Lei ShiDepartment of Burns and Plastic Surgery, The Hospital Affiliated to Jiangsu Universitity, Jiangsu, China.
Shengwu LiaoSchool of Public Health, Southern Medical University, Guangdong, China.
Southern Medical University · CNChinese PLA General Hospital · CNJiangsu University · CNNanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To study the effect of IL-5 on the immune response and lung injury in rats with sepsis. We constructed a rat model of sepsis by cecal ligation and puncture (CLP). The rats were randomly divided into the control group, the sham group, the CLP group and the IL-5 group, with 6 rats in each group. With the induction of CLP, the lung tissue of rats was severely injured, and the water content of lung tissue was significantly increased. Moreover, the ratio of CD4

Indexed as

Acute Lung InjuryLungAnimalsCytokinesDisease Models, AnimalInterleukin-5MaleRatsRats, Sprague-DawleySepsisCytokinesInterleukin-5acute lung injuryil-5immune responseSepsis

Identifiers

PMID34057015
PMCPMC8806508
OpenAlexW3164878008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.