Evidence map›Paper›PMID 34056750›Full record

ArticleMagnetic resonance in medicine2021

Mapping prostatic microscopic anisotropy using linear and spherical b-tensor encoding: A preliminary study.

Markus Nilsson, Greta Eklund, Filip Szczepankiewicz, Mikael Skorpil, Karin Bryskhe, Carl-Fredrik Westin, Claes Lindh, Lennart Blomqvist, Fredrik Jäderling

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Diffusion MRI of the Body: Beyond PGSE-EPI.Journal of magnetic resonance imaging : JMRI · 2026
    Review
  2. Article
  3. Review
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  5. Article
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  9. MRI-based virtual pathology of the prostate.Magma (New York, N.Y.) · 2024
    Review
  10. Article
  11. Article
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  13. Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Markus NilssonClinical Sciences Lund, Radiology, Lund University, Lund, Sweden.ORCID 0000-0002-3140-8223
Greta EklundRandom Walk Imaging AB, Lund, Sweden.
Filip SzczepankiewiczClinical Sciences Lund, Medical Radiation Physics, Lund University, Lund, Sweden.ORCID 0000-0002-5251-587X
Mikael SkorpilDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Karin BryskheRandom Walk Imaging AB, Lund, Sweden.
Carl-Fredrik WestinBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Claes LindhDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Lennart BlomqvistDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Fredrik JäderlingDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Karolinska University Hospital · SELaboratoire d’Imagerie Biomédicale · FRLund University · SEBrigham and Women's Hospital · USKarolinska Institutet · SE

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON, WESTIN, CARL-FREDRIK · 2012 to 2022
$20.9M
Novel DT-MRI Analyses of White Matter in SchizophreniaR01MH074794 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI WESTIN, CARL-FREDRIK · 2007 to 2021
$9.6M
Cancerfonden 2019/474NIBIB NIH HHS P41 EB015902NIMH NIH HHS R01 MH074794Random Walk Imaging MN15Vetenskapsrådet 2016-03443Vetenskapsrådet 2020-04549
6 · The paper itself

Abstract

purposeTensor-valued diffusion encoding provides more specific information than conventional diffusion-weighted imaging (DWI), but has mainly been applied in neuroimaging studies. This study aimed to assess its potential for the imaging of prostate cancer (PCa).

methodsSeventeen patients with histologically proven PCa were enrolled. DWI of the prostate was performed with linear and spherical tensor encoding using a maximal b-value of 1.5 ms/µm

resultsDWI with linear and spherical encoding yielded different image contrasts at high b-values, which enabled the estimation of MK

conclusionTensor-valued diffusion encoding enabled mapping of MK

Indexed as

ProstateProstatic NeoplasmsAnisotropyDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingHumansMaleNeoplasm Gradingdiffusion-weighted imagingheterogeneitymicroscopic anisotropyprostate cancertensor-valued diffusion encoding

Identifiers

PMID34056750
PMCPMC9272946
OpenAlexW3164646106

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.