Evidence map›Paper›PMID 34056679›Full record

ArticleGeroScience2021

Aerobic fitness is inversely associated with neurohemodynamic transduction and blood pressure variability in older adults.

Myles W O'Brien, Diane J Ramsay, Carley D O'Neill, Jennifer L Petterson, Shilpa Dogra, Said Mekary, Derek S Kimmerly

Open access · greenAbstract read
In one paragraph

Article in GeroScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Individuals with posttraumatic stress disorder have increased beat-to-beat blood pressure variability.American journal of physiology. Regulatory, integrative and comparative physiology · 2026
    Article
  2. Article
  3. Article
  4. Augmented resting beat-to-beat blood pressure variability in patients with chronic kidney disease.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023
    Article
  5. Article
  6. Comparison of signal-averaging and regression approaches to analyzing sympathetic transduction.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Article
  7. Article
  8. Impact of sampling duration on spontaneous sympathetic transduction.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Article
  9. Sympathetic neurohemodynamic transduction is attenuated in older males independent of aerobic fitness.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Myles W O'BrienAutonomic Cardiovascular Control and Exercise Laboratory, Division of Kinesiology, School of Health and Human Performance, Faculty of Health, Dalhousie University, 6230 South Street, Halifax, NS, B3H 4R2, Canada.
Diane J RamsayAutonomic Cardiovascular Control and Exercise Laboratory, Division of Kinesiology, School of Health and Human Performance, Faculty of Health, Dalhousie University, 6230 South Street, Halifax, NS, B3H 4R2, Canada.
Carley D O'NeillExercise Physiology and Cardiovascular Health Lab, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Jennifer L PettersonAutonomic Cardiovascular Control and Exercise Laboratory, Division of Kinesiology, School of Health and Human Performance, Faculty of Health, Dalhousie University, 6230 South Street, Halifax, NS, B3H 4R2, Canada.
Shilpa DograSchool of Kinesiology, Acadia University, Wolfville, NS, Canada.
Said MekarySchool of Kinesiology, Acadia University, Wolfville, NS, Canada.
Derek S KimmerlyAutonomic Cardiovascular Control and Exercise Laboratory, Division of Kinesiology, School of Health and Human Performance, Faculty of Health, Dalhousie University, 6230 South Street, Halifax, NS, B3H 4R2, Canada. dskimmerly@dal.ca.ORCID http://orcid.org/0000-0002-3462-8037
Dalhousie University · CAAcadia University · CAOntario Tech University · CAUniversity of Ottawa · CA

Funding

Department of Health
6 · The paper itself

Abstract

Higher aerobic fitness is independently associated with better cardiovascular health in older adults. The transduction of muscle sympathetic nerve activity (MSNA) into mean arterial pressure (MAP) responses provides important insight regarding beat-by-beat neural circulatory control. Aerobic fitness is negatively associated with peak MAP responses to spontaneous MSNA in young males. Whether this relationship exists in older adults is known. We tested the hypothesis that aerobic fitness was inversely related to sympathetic neurohemodynamic transduction and blood pressure variability (BPV) in older adults. Relative peak oxygen consumption (V̇O

Indexed as

Cardiovascular SystemSympathetic Nervous SystemAgedBlood PressureHeart RateHumansMaleMuscle, SkeletalAverage real variability indexCardiorespiratory fitnessMicroneurographyNeurovascular ageing

Identifiers

PMID34056679
PMCPMC8602429
OpenAlexW3164731334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.