Evidence map›Paper›PMID 34056566›Full record

ArticleiScience2021

SARS-CoV-2 seroprevalence in the urban population of Qatar: An analysis of antibody testing on a sample of 112,941 individuals.

Peter V Coyle, Hiam Chemaitelly, Mohamed Ali Ben Hadj Kacem, Naema Hassan Abdulla Al Molawi, Reham Awni El Kahlout, Imtiaz Gilliani, Nourah Younes, Ghada Ali A A Al Anssari, Zaina Al Kanaani, Abdullatif Al Khal and 14 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 99 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 7 institutions in 3 countries.

Peter V CoyleHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Hiam ChemaitellyInfectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Qatar Foundation - Education City, P.O. Box 24144, Doha, Qatar.
Mohamed Ali Ben Hadj KacemHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Naema Hassan Abdulla Al MolawiHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Reham Awni El KahloutHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Imtiaz GillianiHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Nourah YounesHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Ghada Ali A A Al AnssariHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Zaina Al KanaaniHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Abdullatif Al KhalHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Einas Al KuwariHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Adeel A ButtHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Andrew JeremijenkoHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Anvar Hassan KaleeckalHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Ali Nizar LatifHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Riyazuddin Mohammad ShaikHamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
Hanan F Abdul RahimCollege of Health Sciences, QU Health, Qatar University, Doha, P.O. Box 2713, Qatar.
Gheyath K NasrallahBiomedical Research Center, Qatar University, Doha, P.O. Box 2713, Qatar.
Hadi M YassineBiomedical Research Center, Qatar University, Doha, P.O. Box 2713, Qatar.
Mohamed Ghaith Al KuwariPrimary Health Care Corporation, Doha, P.O. Box 26555, Qatar.
Hamad Eid Al RomaihiMinistry of Public Health, Doha, P.O. Box 42, Qatar.
Mohamed H Al-ThaniMinistry of Public Health, Doha, P.O. Box 42, Qatar.
Roberto BertolliniMinistry of Public Health, Doha, P.O. Box 42, Qatar.
Laith J Abu-RaddadInfectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Qatar Foundation - Education City, P.O. Box 24144, Doha, Qatar.
Hamad Medical Corporation · QAMinistry of Public Health · QAQatar University · QACornell University · USPrimary Health Care · QAQueen's University Belfast · GBWeill Cornell Medical College in Qatar · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study objective was to the assess level of detectable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the urban population of Qatar. Antibody testing was performed on residual blood specimens for 112,941 individuals (∼10% of Qatar's urban population) attending for routine/other clinical care between May 12 and September 9, 2020. Seropositivity was 13.3% (95% confidence interval [CI] = 13.1-13.6%) and was independently associated with sex, age, nationality, clinical care encounter type, and testing date. Median optical density (antibody titer) among antibody-positive persons was 27.0 (range = 1.0-150.0), with higher values associated with age, nationality, clinical care encounter type, and testing date. Seropositivity by nationality was positively correlated with the likelihood of having higher antibody titers (Pearson correlation coefficient = 0.85; 95% CI = 0.47-0.96). Less than two in every 10 individuals in Qatar's urban population had detectable antibodies against SARS-CoV-2, suggesting this population is still far from herd immunity and at risk of subsequent infection waves. Higher antibody titer appears to be a biomarker of repeated exposures to the infection.

Indexed as

Health informaticsImmunologyInfection control in health technologyPublic health

Identifiers

PMID34056566
PMCPMC8142077
OpenAlexW3164336383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.