Evidence map›Paper›PMID 34056354›Full record

ArticleACS omega2021

Enhancement of Solubility, Purification, and Inclusion Body Refolding of Active Human Mitochondrial Aldehyde Dehydrogenase 2.

Tingting Zhao, Hui Huang, Peizhu Tan, Yanze Li, Xiuchen Xuan, Fenglan Li, Yuchen Zhao, Yuwei Cao, Zhaojing Wu, Yu Jiang and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Tingting ZhaoDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Hui HuangDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Peizhu TanDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Yanze LiDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Xiuchen XuanDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Fenglan LiDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Yuchen ZhaoDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Yuwei CaoDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Zhaojing WuDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Yu JiangDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Yuanyuan ZhaoDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Aimiao YuDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Kuo WangDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Jiaran XuDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Lingyun ZhouDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.ORCID 0000-0001-6504-2365
Dan YangDepartment of Biochemistry and Molecular Biology, Harbin Medical University, Harbin 150081, China.
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial aldehyde dehydrogenase 2 (ALDH2) is predominantly linked with acetaldehyde detoxification in the second stage of alcohol metabolism. To intensively study ALDH2 function, a higher purity and uniform composition of the protein is required. An efficient

Identifiers

PMID34056354
PMCPMC8154035
OpenAlexW3158742177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.