Evidence map›Paper›PMID 34056249›Full record

ArticleACS omega2021

Controlling Surface-Induced Platelet Activation by Agarose and Gelatin-Based Hydrogel Films.

Gurunath Apte, Annerose Lindenbauer, Jörg Schemberg, Holger Rothe, Thi-Huong Nguyen

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gurunath ApteJunior Research Group, Department of Bioprocess Technique, and Department of Biomaterials, Institute for Bioprocessing and Analytical Measurement Techniques (iba), Rosenhof, 37308 Heilbad Heiligenstadt, Germany.ORCID 0000-0002-4391-2152
Annerose LindenbauerJunior Research Group, Department of Bioprocess Technique, and Department of Biomaterials, Institute for Bioprocessing and Analytical Measurement Techniques (iba), Rosenhof, 37308 Heilbad Heiligenstadt, Germany.
Jörg SchembergJunior Research Group, Department of Bioprocess Technique, and Department of Biomaterials, Institute for Bioprocessing and Analytical Measurement Techniques (iba), Rosenhof, 37308 Heilbad Heiligenstadt, Germany.
Holger RotheJunior Research Group, Department of Bioprocess Technique, and Department of Biomaterials, Institute for Bioprocessing and Analytical Measurement Techniques (iba), Rosenhof, 37308 Heilbad Heiligenstadt, Germany.
Thi-Huong NguyenJunior Research Group, Department of Bioprocess Technique, and Department of Biomaterials, Institute for Bioprocessing and Analytical Measurement Techniques (iba), Rosenhof, 37308 Heilbad Heiligenstadt, Germany.ORCID 0000-0002-9237-3482
Institute for Bioprocessing and Analytical Measurement Techniques · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platelet-surface interaction is of paramount importance in biomedical applications as well as in vitro studies. However, controlling platelet-surface activation is challenging and still requires more effort as they activate immediately when contacting with any nonphysiological surface. As hydrogels are highly biocompatible, in this study, we developed agarose and gelatin-based hydrogel films to inhibit platelet-surface adhesion. We found promising agarose films that exhibit higher surface wettability, better controlled-swelling properties, and greater stiffness compared to gelatin, resulting in a strong reduction of platelet adhesion. Mechanical properties and surface wettability of the hydrogel films were varied by adding magnetite (Fe

Identifiers

PMID34056249
PMCPMC8153948
OpenAlexW3155636981

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.