Evidence map›Paper›PMID 34056083›Full record

ArticleACS central science2021

A Comprehensive Review of the Global Efforts on COVID-19 Vaccine Development.

Yingzhu Li, Rumiana Tenchov, Jeffrey Smoot, Cynthia Liu, Steven Watkins, Qiongqiong Zhou

Abstract readNews
In one paragraph

Article in ACS central science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

180 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
  4. Pooled it
  5. Polypharmacy among COVID-19 patients: A systematic review.Journal of the American Pharmacists Association : JAPhA
    Pooled it
  6. PERFECTA Loaded Lipid Cubosomes forChemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
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  16. ACS central science · 2025
    Article
  17. Review
  18. Article
  19. Review
  20. Article

120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yingzhu LiCAS, a division of the American Chemical Society, 2540 Olentangy River Road, Columbus, Ohio 43210-3012, United States.ORCID 0000-0002-4946-7272
Rumiana TenchovCAS, a division of the American Chemical Society, 2540 Olentangy River Road, Columbus, Ohio 43210-3012, United States.ORCID 0000-0003-4698-6832
Jeffrey SmootCAS, a division of the American Chemical Society, 2540 Olentangy River Road, Columbus, Ohio 43210-3012, United States.
Cynthia LiuCAS, a division of the American Chemical Society, 2540 Olentangy River Road, Columbus, Ohio 43210-3012, United States.ORCID 0000-0003-3858-1501
Steven WatkinsCAS, a division of the American Chemical Society, 2540 Olentangy River Road, Columbus, Ohio 43210-3012, United States.
Qiongqiong ZhouCAS, a division of the American Chemical Society, 2540 Olentangy River Road, Columbus, Ohio 43210-3012, United States.ORCID 0000-0001-6711-369X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report examines various vaccine platforms including inactivated vaccines, protein-based vaccines, viral vector vaccines, and nucleic acid (DNA or mRNA) vaccines, and their ways of producing immunogens in cells.

Identifiers

PMID34056083
PMCPMC8029445

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.