ArticleFrontiers in molecular biosciences2021
Understanding Systemic and Local Inflammation Induced by Nasal Polyposis: Role of the Allergic Phenotype.
Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Multi-omics integration in allergy, viral infections and asthma: a comprehensive analysis of bioinformatics tools.Frontiers in bioinformatics · 2026Article
- Microdebrider Assisted Endoscopic Sinus Surgery Versus Conventional Endoscopic Sinus Surgery in Management of Sinonasal Polyposis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Unveiling the Impact of Total Body Fluid Dynamics on Chronic Rhinosinusitis With Sinonasal Polyposis.Cureus · 2025Article
- Treatment Strategy of Uncontrolled Chronic Rhinosinusitis with Nasal Polyps: A Review of Recent Evidence.International journal of molecular sciences · 2023Review
- Comparative study of clinical symptoms of chronic rhinosinusitis with nasal polyps patients.Immunity, inflammation and disease · 2023Observational
- Development of a Novel Targeted Metabolomic LC-QqQ-MS Method in Allergic Inflammation.Metabolites · 2022Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by persistent symptoms associated to the development of nasal polyps. To this day, the molecular mechanisms involved are still not well defined. However, it has been suggested that a sustained inflammation as allergy is involved in its onset. In this exploratory study, the aim was to investigate the effect of the allergic status in the development of CRSwNP. To achieve this, we recruited 22 patients with CRSwNP and classified them in non-allergic and allergic using ImmunoCAP ISAC molecular diagnosis. Plasma samples were analyzed using liquid chromatography coupled to mass spectrometry (LC-MS). Subsequently, significant metabolites from plasma that were commercially available were then analyzed by targeted analysis in some nasal polyps. Additionally, nasal polyp and nasal mucosa samples were examined for eosinophils, neutrophils, CD3
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Registered trials
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