Evidence map›Paper›PMID 34055782›Full record

ArticleFrontiers in cell and developmental biology2021

JMJD6 Dysfunction Due to Iron Deficiency in Preeclampsia Disrupts Fibronectin Homeostasis Resulting in Diminished Trophoblast Migration.

Sruthi Alahari, Abby Farrell, Leonardo Ermini, Chanho Park, Julien Sallais, Sarah Roberts, Taylor Gillmore, Michael Litvack, Martin Post, Isabella Caniggia

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Versatile JMJD proteins: juggling histones and much more.Trends in biochemical sciences · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Sruthi AlahariLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Abby FarrellLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Leonardo ErminiLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Chanho ParkLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Julien SallaisLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Sarah RobertsLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Taylor GillmoreLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Michael LitvackProgram in Translational Medicine, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, ON, Canada.
Martin PostDepartment of Physiology, University of Toronto, Toronto, ON, Canada.
Isabella CaniggiaLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Lunenfeld-Tanenbaum Research Institute · CASinai Health System · CAHospital for Sick Children · CAUniversity of Toronto · CA

Funding

Lipidomics: A Novel Tool to Define Human Placental Development and Function Across PregnancyR01HD089660 · NICHD · SINAI HEALTH SYSTEM · PI CANIGGIA, ISABELLA · 2016 to 2020
$1.9M
NICHD NIH HHS R01 HD089660
6 · The paper itself

Abstract

The mechanisms contributing to excessive fibronectin in preeclampsia, a pregnancy-related disorder, remain unknown. Herein, we investigated the role of JMJD6, an O

Indexed as

fibronectinironJMJD6pMSCspreeclampsiatrophoblast migration

Identifiers

PMID34055782
PMCPMC8149756
OpenAlexW3163379366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.