Evidence map›Paper›PMID 34055774›Full record

ArticleFrontiers in cell and developmental biology2021

Adipose-Derived Stem Cells Promote Bone Coupling in Bisphosphonate-Related Osteonecrosis of the Jaw by TGF-β1.

Xian Dong, Linhai He, Xiaolong Zang, Yang He, Jingang An, Baoping Wu, Xinhua Liu, Hongsen Bi, Yi Zhang, E Xiao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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  11. Oxidative medicine and cellular longevity · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xian DongDepartment of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Linhai HeDepartment of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Xiaolong ZangDepartment of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Yang HeDepartment of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Jingang AnDepartment of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Baoping WuThe First People's Hospital of Jinzhong, Jinzhong, China.
Xinhua LiuThe First People's Hospital of Jinzhong, Jinzhong, China.
Hongsen BiDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Yi ZhangDepartment of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
E XiaoDepartment of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Peking University · CNSecond People 's Hospital of Jinzhong · CNPeking University Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate molecularly targeted therapy to revive bone remodeling and prevent BRONJ by local adipose-derived stem cells (ADSCs) transplantation. Clinical samples of BRONJ and healthy jawbones were used to examine the bone coupling-related cells and TGF-β1 expression. Bone coupling-related cells and TGF-β1 expression were also assessed in BRONJ-like animal model to confirm the results in clinical samples. ADSCs were locally administered

Indexed as

adipose-derived mesenchymal stem cellsbisphosphonate-related osteonecrosis of the jaw (BRONJ)bone remodelingosteoclaststransforming growth factor beta1zoledronic acid

Identifiers

PMID34055774
PMCPMC8154543
OpenAlexW3162851668

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.