Evidence map›Paper›PMID 34055744›Full record

ReviewFrontiers in chemistry2021

The Potential Application of Magnetic Nanoparticles for Liver Fibrosis Theranostics.

Aziz Eftekhari, Allahveirdy Arjmand, Ayyub Asheghvatan, Helena Švajdlenková, Ondrej Šauša, Huseyn Abiyev, Elham Ahmadian, Oleh Smutok, Rovshan Khalilov, Taras Kavetskyy and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  5. Nanoemulsions ofAntioxidants (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 8 countries.

Aziz EftekhariMaragheh University of Medical Sciences, Maragheh, Iran.
Allahveirdy ArjmandMaragheh University of Medical Sciences, Maragheh, Iran.
Ayyub AsheghvatanMaragheh University of Medical Sciences, Maragheh, Iran.
Helena ŠvajdlenkováPolymer Institute, Slovak Academy of Sciences, Bratislava, Slovakia.
Ondrej ŠaušaInstitute of Physics, Slovak Academy of Sciences, Bratislava, Slovakia.
Huseyn AbiyevDepartment of Biochemistry, Azerbaijan Medical University, Baku, Azerbaijan.
Elham AhmadianKidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Oleh SmutokDepartment of Chemistry and Biomolecular Science, Clarkson University, Potsdam, NY, United States.
Rovshan KhalilovRussian Institute for Advanced Study, Moscow State Pedagogical University, Moscow, Russian Federation.
Taras KavetskyyDepartment of Surface Engineering, The John Paul II Catholic University of Lublin, Lublin, Poland.
Magali CucchiariniCenter of Experimental Orthopaedics, Saarland University Medical Center, Homburg, Germany.
University of Maragheh · IRAzerbaijan Medical University · AZAzerbaijan National Academy of Sciences · AZComenius University Bratislava · SKNational Academy of Sciences of Ukraine · UAPolymer Institute of the Slovak Academy of Sciences · SKSaarland University · DESlovak Academy of Sciences · SKTabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver fibrosis is a major cause of morbidity and mortality worldwide due to chronic liver damage and leading to cirrhosis, liver cancer, and liver failure. To date, there is no effective and specific therapy for patients with hepatic fibrosis. As a result of their various advantages such as biocompatibility, imaging contrast ability, improved tissue penetration, and superparamagnetic properties, magnetic nanoparticles have a great potential for diagnosis and therapy in various liver diseases including fibrosis. In this review, we focus on the molecular mechanisms and important factors for hepatic fibrosis and on potential magnetic nanoparticles-based therapeutics. New strategies for the diagnosis of liver fibrosis are also discussed, with a summary of the challenges and perspectives in the translational application of magnetic nanoparticles from bench to bedside.

Indexed as

drug deliveryliver fibrosismagnetic nanoparticlesnanomedicinetheranostics

Identifiers

PMID34055744
PMCPMC8161198
OpenAlexW3162648630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.