Evidence map›Paper›PMID 34055734›Full record

ArticleFrontiers in chemistry2021

Engineering Promiscuous Alcohol Dehydrogenase Activity of a Reductive Aminase

Hao-Yu Jia, Zi-Yue Yang, Qi Chen, Min-Hua Zong, Ning Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Structure of the imine reductase from Ajellomyces dermatitidis in three crystal forms.Acta crystallographica. Section F, Structural biology communications · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hao-Yu JiaSchool of Food Science and Engineering, South China University of Technology, Guangzhou, China.
Zi-Yue YangSchool of Food Science and Engineering, South China University of Technology, Guangzhou, China.
Qi ChenState Key Laboratory of Bioreactor Engineering, Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, Shanghai, China.
Min-Hua ZongSchool of Food Science and Engineering, South China University of Technology, Guangzhou, China.
Ning LiSchool of Food Science and Engineering, South China University of Technology, Guangzhou, China.
South China University of Technology · CNEast China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Catalytic promiscuity is a promising starting point for improving the existing enzymes and even creating novel enzymes. In this work, site-directed mutagenesis was performed to improve promiscuous alcohol dehydrogenase activity of reductive aminase from

Indexed as

alcohol dehydrogenasesbiobased furanscatalytic promiscuityprotein engineeringreductive aminases

Identifiers

PMID34055734
PMCPMC8155666
OpenAlexW3162416028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.