Evidence map›Paper›PMID 34055669›Full record

ReviewFrontiers in cellular and infection microbiology2021

The Role of Sialic Acids in the Establishment of Infections by Pathogens, With Special Focus on

Tainá Cavalcante, Mariana Medina Medeiros, Simon Ngao Mule, Giuseppe Palmisano, Beatriz Simonsen Stolf

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Exploring CD169Vaccines · 2025
    Review
  5. Observational
  6. Article
  7. Review
  8. Article
  9. Total serumiScience · 2023
    Article
  10. Review
  11. Review
  12. Review
  13. RSC chemical biology · 2022
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tainá CavalcanteLaboratory of Leishmaniasis, Department of Parasitology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Mariana Medina MedeirosLaboratory of Leishmaniasis, Department of Parasitology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Simon Ngao MuleGlycoProteomics Laboratory, Department of Parasitology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Giuseppe PalmisanoGlycoProteomics Laboratory, Department of Parasitology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Beatriz Simonsen StolfLaboratory of Leishmaniasis, Department of Parasitology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbohydrates or glycans are ubiquitous components of the cell surface which play crucial biological and structural roles. Sialic acids (Sias) are nine-carbon atoms sugars usually present as terminal residues of glycoproteins and glycolipids on the cell surface or secreted. They have important roles in cellular communication and also in infection and survival of pathogens. More than 20 pathogens can synthesize or capture Sias from their hosts and incorporate them into their own glycoconjugates and derivatives. Sialylation of pathogens' glycoconjugates may be crucial for survival inside the host for numerous reasons. The role of Sias in protozoa such as

Indexed as

LeishmaniaLeishmaniasisGlycoconjugatesHumansSialic Acid Binding Immunoglobulin-like LectinsSialic AcidsGlycoconjugatesSialic Acid Binding Immunoglobulin-like LectinsSialic Acidshost-pathogeninfectionLeishmaniasialic acidsSiglec

Identifiers

PMID34055669
PMCPMC8155805
OpenAlexW3162639071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.