Evidence map›Paper›PMID 34055396›Full record

ArticleJournal of ophthalmology2021

Effect of Topical Brimonidine 0.15% on Conjunctival Injection after Strabismus Surgery in Children.

Dong Hyun Kim, Hee Kyung Yang, Sang Beom Han, Jeong-Min Hwang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05480098 (Efficacy of Intraoperative Brimonidine for Hemostasis During Eyelid Surgery), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05480098 phase4withdrawnnot on this mapstarted 2022, after this paper: background citation

Efficacy of Intraoperative Brimonidine for Hemostasis During Eyelid Surgery

TypeinterventionalSponsorUniversity of LouisvilleRan2022 to 2024Enrolled0ConditionsDermatochalasis of Eyelid, Ptosis, Eyelid, Ectropion, EntropionArmsBrimonidine Topical
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dong Hyun KimDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.ORCID https://orcid.org/0000-0003-3179-3122
Hee Kyung YangDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.ORCID https://orcid.org/0000-0002-1140-6036
Sang Beom HanDepartment of Ophthalmology, Kangwon National University College of Medicine, Kangwon National University Hospital, Chuncheon, Kangwon, Republic of Korea.ORCID https://orcid.org/0000-0002-3931-239X
Jeong-Min HwangDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.ORCID https://orcid.org/0000-0003-0837-2864
Seoul National University Bundang Hospital · KRKangwon National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the effects of topical brimonidine 0.15% instillation on conjunctival injection after strabismus surgery in children.

methodsWe retrospectively analyzed 63 Korean children who underwent strabismus surgery for intermittent exotropia. Patients received topical brimonidine 0.15% after surgery for up to 4 weeks. Conjunctival injection was objectively assessed using a software that automatically scored the region of interest from the image of the bulbar conjunctiva. Conjunctival injection scores were compared with those of the control group who were not prescribed topical brimonidine.

resultsThe mean scores of conjunctival injection after rectus muscle recession and resection were significantly lower in the brimonidine group than the controls at 4 weeks after surgery (

conclusionsAdministration of topical brimonidine 0.15% after strabismus surgery is efficacious and safe in reducing postoperative conjunctival injection.

Identifiers

PMID34055396
PMCPMC8112999
OpenAlexW3165168102

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.