Evidence map›Paper›PMID 34055345›Full record

ArticleMolecular and clinical oncology2021

Postoperative solitary liver metastasis from esophageal squamous cell carcinoma achieving a clinical complete response to chemotherapy with cisplatin and 5-fluorouracil followed by stereotactic body radiotherapy: A case report.

Shuichi Fukuda, Kaoru Okajima, Kaoru Okada, Kohei Fukuda, Tomoko Wakasa, Tomoyuki Tsujimoto, Atsushi Gakuhara, Hideo Tomihara, Katsuya Ohta, Kotaro Kitani and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Shuichi FukudaDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Kaoru OkajimaDepartment of Radiology, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Kaoru OkadaDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Kohei FukudaDepartment of Radiology, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Tomoko WakasaDepartment of Pathology, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Tomoyuki TsujimotoDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Atsushi GakuharaDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Hideo TomiharaDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Katsuya OhtaDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Kotaro KitaniDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Kazuhiko HashimotoDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Hajime IshikawaDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Jin-Ichi HidaDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Masao YukawaDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Yoshio OhtaDepartment of Pathology, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Masatoshi InoueDepartment of Gastroenterological Surgery, Kindai University Nara Hospital, Ikoma, Nara 630-0293, Japan.
Kindai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment strategies for distant organ metastasis have changed markedly since the concept of oligometastasis was introduced. The perception that distant organ metastasis is a systemic disease and not eligible for local therapy is now a thing of the past. Therefore, the present report details a case of postoperative solitary liver metastasis from esophageal squamous cell carcinoma (ESCC), which achieved a clinical complete response to chemotherapy with cisplatin and 5-fluorouracil (5-FU) followed by stereotactic body radiotherapy (SBRT). A 76-year-old male patient underwent esophagectomy for lower thoracic ESCC. At 7 months after surgery, abdominal CT revealed a solitary hypovascular mass, 28 mm in size, in segment 7 of the liver. After three courses of chemotherapy with cisplatin and 5-FU, abdominal CT revealed that the liver mass had shrunk to 7 mm in size. SBRT was then administered with a 6 MV X-ray beam generated by a linear accelerator. A total dose of 50 Gy was given in 5 fractions of 10 Gy to the liver mass. At 1 month after SBRT, abdominal CT revealed that the liver mass had disappeared. The patient received no further adjuvant chemotherapy and had no recurrence at 18 months after diagnosis of liver metastasis and 13 months after SBRT.

Indexed as

esophageal cancerliver metastasesoligometastasisoligorecurrencestereotactic ablative radiotherapy

Identifiers

PMID34055345
PMCPMC8138851
OpenAlexW3158895497

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.