ArticleToxicology research2019
Thyroid endocrine status and biochemical stress responses in adult male Wistar rats chronically exposed to pristine polystyrene nanoplastics.
Article in Toxicology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 81 citations in OpenAlex.
- Micro/nanoplastics induce thyroid follicular cell pyroptosis to trigger thyrotoxicity by activating NF-κB signaling.Annals of medicine · 2026Article
- Histopathological, Biochemical and Molecular Investigations on the Potential Endocrine Disruption of Polystyrene Nanoparticles in Adult Male Albino Rats.Environmental toxicology · 2026Article
- Environmental Micro(nano)plastic Exposure and Associated Human Health Risks: A Comprehensive Review.Toxics · 2026Review
- Review
- Adverse adult-onset and multigenerational effects in zebrafish (Danio rerio) developmentally exposed to polystyrene nanoplastics.Environmental pollution (Barking, Essex : 1987) · 2025Article
- Polystyrene Microplastics-Induced Thyroid Dysfunction in Mice: A Study of Gene Expression, Oxidative Stress, and Histopathological Changes.Veterinary medicine and science · 2025Article
- Nanoplastics as Gene and Epigenetic Modulators of Endocrine Functions: A Perspective.International journal of molecular sciences · 2025Review
- The Effects of Microplastics on Musculoskeletal Disorder; A Narrative Review.Current reviews in musculoskeletal medicine · 2025Review
- Protective effect of Cordycepin on blood-testis barrier against pre-puberty polystyrene nanoplastics exposure in male rats.Particle and fibre toxicology · 2024Article
- Detrimental consequences of micropolymers associated plasticizers on endocrinal disruption.Materials today. Bio · 2024Review
- The impact of environmental factors and contaminants on thyroid function and disease from fetal to adult life: current evidence and future directions.Frontiers in endocrinology · 2024Review
- Micro- and nanoplastics (MNPs) and their potential toxicological outcomes: State of science, knowledge gaps and research needs.NanoImpact · 2023Review
- Nanoparticles-induced potential toxicity on human health: Applications, toxicity mechanisms, and evaluation models.MedComm · 2023Review
- Histological, haematological, and thyroid hormones toxicity of female rats orally exposed to CuO/ZnO core/shell nanoparticles synthesized by Ar plasma jets.Archives of toxicology · 2023Article
- Short- and long-term polystyrene nano- and microplastic exposure promotes oxidative stress and divergently affects skin cell architecture and Wnt/beta-catenin signaling.Particle and fibre toxicology · 2023Article
- Review
- Impact of polystyrene microplastic exposure on lipid profile and oxidative stress status of male and female Wistar rats.Environmental analysis, health and toxicology · 2022Article
- Enhancement of antibacterial activity through phyto-fabrication of silver nanoparticles with Ficus thonningii aqueous extracts.IET nanobiotechnology · 2022Article
- Consequences of nano and microplastic exposure in rodent models: the known and unknown.Particle and fibre toxicology · 2022Review
- Screening for polystyrene nanoparticle toxicity on kidneys of adult male albino rats using histopathological, biochemical, and molecular examination results.Cell and tissue research · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Toxicity evaluations of micro- or nano-sized plastics in rodent species commonly employed for toxicity analyses based on which risk assessment for humans could be performed are still largely lacking. Given this knowledge gap, the present work was aimed at determining the potential impact of chronic exposure to polystyrene nanoplastics (PS NPs) on the thyroid endocrine status and biochemical stress in a rat model. Young adult male rats were orally administered with PS NPs (1, 3, 6 and 10 mg kg
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.