Evidence map›Paper›PMID 34055072›Full record

ReviewExperimental and therapeutic medicine2021

Tumoral markers in bladder cancer (Review).

Ovidiu Bratu, Dragos Marcu, Radu Anghel, Dan Spinu, Lucian Iorga, Irina Balescu, Nicolae Bacalbasa, Camelia Diaconu, Cornel Savu, Carmen Savu and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ovidiu BratuDepartment of Urology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Dragos MarcuDepartment of Urology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Radu AnghelDepartment of Urology, University Emergency Central Military Hospital, 010825 Bucharest, Romania.
Dan SpinuDepartment of Urology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Lucian IorgaDepartment of Urology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Irina BalescuDepartment of Visceral Surgery, 'Ponderas' Academic Hospital, 021188 Bucharest, Romania.
Nicolae BacalbasaDepartment of Obstetrics and Gynecology, 'Carol Davila' University of Medicine and Pharmacy, 023991 Bucharest, Romania.
Camelia DiaconuDepartment of Internal Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Cornel SavuDepartment of Thoracic Surgery, 'Marius Nasta' National Institute of Pneumophtisiology, 050159 Bucharest, Romania.
Carmen SavuDepartment of Anesthesiology, 'Fundeni' Clinical Institute, 022328 Bucharest, Romania.
Alexandru CherciuDepartment of Urology, University Emergency Central Military Hospital, 010825 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROInstitutul Clinic Fundeni · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder tumors are frequently diagnosed urologic malignant diseases with an extremely high recurrence rate compared to other neoplastic tumors. Urothelial bladder carcinomas are mostly identified in their incipient form, as non-muscle invasive, but despite that, a third of them develop into aggressive recurrent disease. The diagnosis of bladder carcinoma at this moment is established using cytology and cystoscopy and is a great challenge for clinicians due to the lack of sensitivity. Urinary biomarkers could improve and enhance the diagnosis and screening techniques and determine a more accurate recurrence rate. However, bladder cancer is a heterogeneous disease and the existence of a single marker test with reduced cost is unlikely; thus, until then, the use of a panel of markers to obtain valuable information is inevitable even though suboptimal for use. To improve this deadlock, new biomarker panels should be identified and prepared to equalize the cost-efficiency balance. The present paper is a literature review concerning the most commonly used tumor markers in urinary bladder cancer as well as the most commonly encountered genetic modifications in such patients.

Indexed as

cystoscopycytologynon-muscle invasiveurinary biomarkersurothelial bladder carcinoma

Identifiers

PMID34055072
PMCPMC8145526
OpenAlexW3161590770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.