Evidence map›Paper›PMID 34055062›Full record

ArticleExperimental and therapeutic medicine2021

Comparative hematological profiles for dose-dense vs. regular anthracycline-based neoadjuvant chemotherapy in non-metastatic breast cancer.

Dorel Popovici, Cristina Oprean, Sorin Săftescu, Alina Negru, Mihnea Munteanu, Horia T Stanca, Adrian Teodoru, Simona Stanca, Șerban Negru

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Dorel PopoviciDepartment of Oncology, 'Victor Babeş' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Cristina OpreanDepartment of Pathology, 'Victor Babeş' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Sorin SăftescuDepartment of Oncology, 'Victor Babeş' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Alina NegruDepartment of Cardiology, 'Victor Babeş' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Mihnea MunteanuDepartment of Ophthalmology, 'Victor Babeş' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Horia T StancaDepartment of Ophthalmology, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Adrian TeodoruDepartment of Ophthalmology, 'Lucian Blaga' University, 550169 Sibiu, Romania.
Simona StancaDepartment of Pediatrics, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Șerban NegruDepartment of Oncology, 'Victor Babeş' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · ROCarol Davila University of Medicine and Pharmacy · ROLucian Blaga University of Sibiu · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to examine both the feasibility and toxicity of neoadjuvant dose-dense chemotherapy in women with non-metastatic breast cancer. A search within the OncoHelp Association breast cancer database has been performed in order to identify all non-metastatic breast cancer patients who underwent an initial consultation with a medical oncologist between March 2016 and April 2020. The inclusion criteria used were: i) Age, ii) follow-up care obtained at OncoHelp Association, iii) the intent to treat with a neoadjuvant dose-dense anthracycline every two weeks for four cycles (C1-C4) followed by paclitaxel every two weeks for four cycles, with white blood cell growth factor support, and iv) regular anthracycline-based chemotherapy every three weeks for four cycles, followed by paclitaxel every three weeks for four cycles, v) weight, vi) height, vii) Eastern Cooperative Oncology Group (ECOG) performance status, viii) hemoglobin (Hb) level, ix) Platelet count and x) neutrophil count.

Indexed as

anthracyclinebreast cancerchemotherapydose-denseneoadjuvant

Identifiers

PMID34055062
PMCPMC8138269
OpenAlexW3160519388

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.