Evidence map›Paper›PMID 34055023›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Systems Pharmacology and

Zhen-Zhen Wang, Yuan Jia, Kamal D Srivastava, Weihua Huang, Raj Tiwari, Anna Nowak-Wegrzyn, Jan Geliebter, Mingsan Miao, Xiu-Min Li

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  4. Network pharmacology and molecular docking investigation ofJournal of advanced pharmaceutical technology & research
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Zhen-Zhen WangAcademy of Chinese Medical Science, Henan University of Chinese Medicine, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0001-6961-4367
Yuan JiaAcademy of Chinese Medical Science, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Kamal D SrivastavaDepartment of Microbiology & Immunology, New York Medical College, New York 10595, USA.
Weihua HuangDepartment of Pathology, New York Medical College, New York 10595, USA.
Raj TiwariDepartment of Microbiology & Immunology, New York Medical College, New York 10595, USA.
Anna Nowak-WegrzynDepartment of Pediatrics, New York University Langone Health, New York, NY 10029, USA.
Jan GeliebterDepartment of Microbiology & Immunology, New York Medical College, New York 10595, USA.
Mingsan MiaoAcademy of Chinese Medical Science, Henan University of Chinese Medicine, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0003-2681-4291
Xiu-Min LiDepartment of Microbiology & Immunology, New York Medical College, New York 10595, USA.ORCID https://orcid.org/0000-0002-5010-9130
New York Medical College · USFirst Affiliated Hospital of Henan University · CNNYU Langone Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eczema is a complex chronic inflammatory skin disease impacted by environmental factors, infections, immune disorders, and deficiencies in skin barrier function. Shi Zhen Tea (SZT), derived from traditional Chinese medicine Xiao-Feng-San, has shown to be an effective integrative therapy for treating skin lesions, itching, and sleeping loss, and it facilitates reduction of topical steroid and antihistamine use in pediatric and adult patients with severe eczema. Yet, its active compounds and therapeutic mechanisms have not been elucidated. In this study, we sought to investigate the active compounds and molecular mechanisms of SZT in treating eczema using systems pharmacology and

Identifiers

PMID34055023
PMCPMC8143894
OpenAlexW3160033474

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.