Evidence map›Paper›PMID 34055019›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Efficacy of Oral Administration of

Masoumeh Asgharpour, Armin Khavandegar, Parastoo Balaei, Noora Enayati, Parham Mardi, Amirhesam Alirezaei, Mahmood Bakhtiyari

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Frontiers in nutrition · 2023
    Pooled it
  4. Article
  5. Article
  6. Review
  7. Allicin shows antifungal efficacy againstFrontiers in microbiology · 2022
    Article
  8. Effects ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Masoumeh AsgharpourDepartment of Nephrology, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Armin KhavandegarStudent Research Committee, Alborz University of Medical Sciences, Karaj, Iran.
Parastoo BalaeiClinical Research and Development Center, Shahid Modarres Hospital, Department of Nephrology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Noora EnayatiDepartment of Phytochemistry, Medicinal Plants and Drug Research Institute, Shahid Beheshti University, Tehran, Iran.
Parham MardiStudent Research Committee, Alborz University of Medical Sciences, Karaj, Iran.ORCID https://orcid.org/0000-0002-9228-4615
Amirhesam AlirezaeiClinical Research and Development Center, Shahid Modarres Hospital, Department of Nephrology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-9720-6723
Mahmood BakhtiyariNon-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.ORCID https://orcid.org/0000-0002-1216-7671
Jahrom University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRBabol University of Medical Sciences · IRShahid Beheshti University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammation plays a prominent role in the deteriorating cardiovascular risk of hemodialysis patients. Utilization of herbal remedies, especially garlic extract, in these patients has resulted in promising improvement in lipid profile, inflammation, and cardiovascular markers. PURPOSE: In this survey, we aimed to determine the effects of oral administration of

methodsIn this interventional double-blinded randomized crossover study, 70 patients were enrolled and assigned in two groups. Each group received 300 mg of garlic powder BID or placebo for eight weeks; after a six-week wash-out period, the agents were switched between two groups so that the group who received garlic powder in the first eight weeks received placebo for the second eight weeks, and vice versa. Venous blood samples were obtained in baseline, wash-out period, and at the end of study. Following obtaining laboratory data, BUN, creatinine, Na, K, Ca, Ph, homocysteine, and lipid profile were compared.

resultsNo significant differences were shown at baselines of outcomes between the garlic and placebo group (

conclusionIn this study,

Identifiers

PMID34055019
PMCPMC8149222
OpenAlexW3163596367

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.