Evidence map›Paper›PMID 34054943›Full record

ArticleNeural plasticity2021

Altered Functional Connectivity in Children with ADHD Revealed by Scalp EEG: An ERP Study.

Chunli Chen, Huan Yang, Yasong Du, Guangzhi Zhai, Hesheng Xiong, Dezhong Yao, Peng Xu, Jianhua Gong, Gang Yin, Fali Li

Open access · goldAbstract read
In one paragraph

Article in Neural plasticity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. EEG Global Coherence in Scholar ADHD Children during Visual Object Processing.International journal of environmental research and public health · 2022
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Chunli ChenSchool of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China.
Huan YangChina National Clinical Research Center on Mental Disorders (Xiangya), Changsha 410011, China.
Yasong DuMental Health Center Affiliated to Medical School of Shanghai Jiao Tong University, 200030, China.
Guangzhi ZhaiShenzhen Nao Qianneng Co., Ltd., 518002, China.
Hesheng XiongShenzhen Nao Qianneng Co., Ltd., 518002, China.
Dezhong YaoSchool of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China.
Peng XuSchool of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China.ORCID 0000-0002-7932-0386
Jianhua GongLuohu District Maternity and Child Healthcare Hospital, Shenzhen 518019, China.ORCID 0000-0002-2577-1309
Gang YinSichuan Cancer Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China.ORCID 0000-0001-9995-4629
Fali LiSchool of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China.ORCID 0000-0002-2450-4591
University of Electronic Science and Technology of China · CNCentral South University · CNShanghai Jiao Tong University · CNShenzhen Maternity and Child Healthcare Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental brain disorders in childhood. Despite extensive researches, the neurobiological mechanism underlying ADHD is still left unveiled. Since the deficit functions, such as attention, have been demonstrated in ADHD, in our present study, based on the oddball P3 task, the corresponding electroencephalogram (EEG) of both healthy controls (HCs) and ADHD children was first collected. And we then not only focused on the event-related potential (ERP) evoked during tasks but also investigated related brain networks. Although an insignificant difference in behavior was found between the HCs and ADHD children, significant electrophysiological differences were found in both ERPs and brain networks. In detail, the dysfunctional attention occurred during the early stage of the designed task; as compared to HCs, the reduced P2 and N2 amplitudes in ADHD children were found, and the atypical information interaction might further underpin such a deficit. On the one hand, when investigating the cortical activity, HCs recruited much stronger brain activity mainly in the temporal and frontal regions, compared to ADHD children; on the other hand, the brain network showed atypical enhanced long-range connectivity between the frontal and occipital lobes but attenuated connectivity among frontal, parietal, and temporal lobes in ADHD children. We hope that the findings in this study may be instructive for the understanding of cognitive processing in children with ADHD.

Indexed as

ElectroencephalographyEvoked PotentialsAttention Deficit Disorder with HyperactivityCerebral CortexChildChild, PreschoolElectrophysiological PhenomenaFemaleHumansMaleNerve NetPsychomotor PerformanceReaction TimeScalp

Identifiers

PMID34054943
PMCPMC8133851
OpenAlexW3160945557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.