Evidence map›Paper›PMID 34054936›Full record

ArticleInternational journal of biomedical imaging2021

Value CMR: Towards a Comprehensive, Rapid, Cost-Effective Cardiovascular Magnetic Resonance Imaging.

El-Sayed H Ibrahim, Luba Frank, Dhiraj Baruah, V Emre Arpinar, Andrew S Nencka, Kevin M Koch, L Tugan Muftuler, Orhan Unal, Jadranka Stojanovska, Jason C Rubenstein and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biomedical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Society for Cardiovascular Magnetic Resonance recommendations toward environmentally sustainable cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Guideline
  2. Article
  3. Utility of Emergent Spine MRI in the Emergency Department.The western journal of emergency medicine · 2025
    Article
  4. Readability of patient education materials on cardiac magnetic resonance imaging.European heart journal. Imaging methods and practice · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
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  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

El-Sayed H IbrahimMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0003-4292-4669
Luba FrankMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0002-9599-8955
Dhiraj BaruahMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0003-1763-8919
V Emre ArpinarMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0002-3238-4569
Andrew S NenckaMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0001-5268-2718
Kevin M KochMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0003-4490-9761
L Tugan MuftulerMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0002-6635-5678
Orhan UnalUniversity of Wisconsin-Madison, 600 Highland Ave, Madison, WI 53792, USA.ORCID https://orcid.org/0000-0001-7724-6744
Jadranka StojanovskaUniversity of Michigan, 500 S State St., Ann Arbor, MI 48109, USA.ORCID https://orcid.org/0000-0003-2742-6274
Jason C RubensteinMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0003-3028-3876
Sherry-Ann BrownMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0002-5687-7632
John CharlsonMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0003-2426-0029
Elizabeth M GoreMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0001-7807-9060
Carmen BergomMedical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0002-0886-5055
Medical College of Wisconsin · USUniversity of Michigan · USUniversity of Wisconsin–Madison · US

Funding

Genetic Modifiers of Radiation Therapy-Induced CardiotoxicityR01HL147884 · NHLBI · WASHINGTON UNIVERSITY · PI BERGOM, CARMEN · 2019 to 2023
$2.3M
NHLBI NIH HHS R01 HL147884
6 · The paper itself

Abstract

Cardiac magnetic resonance imaging (CMR) is considered the gold standard for measuring cardiac function. Further, in a single CMR exam, information about cardiac structure, tissue composition, and blood flow could be obtained. Nevertheless, CMR is underutilized due to long scanning times, the need for multiple breath-holds, use of a contrast agent, and relatively high cost. In this work, we propose a rapid, comprehensive, contrast-free CMR exam that does not require repeated breath-holds, based on recent developments in imaging sequences. Time-consuming conventional sequences have been replaced by advanced sequences in the proposed CMR exam. Specifically, conventional 2D cine and phase-contrast (PC) sequences have been replaced by optimized 3D-cine and 4D-flow sequences, respectively. Furthermore, conventional myocardial tagging has been replaced by fast strain-encoding (SENC) imaging. Finally, T1 and T2 mapping sequences are included in the proposed exam, which allows for myocardial tissue characterization. The proposed rapid exam has been tested in vivo. The proposed exam reduced the scan time from >1 hour with conventional sequences to <20 minutes. Corresponding cardiovascular measurements from the proposed rapid CMR exam showed good agreement with those from conventional sequences and showed that they can differentiate between healthy volunteers and patients. Compared to 2D cine imaging that requires 12-16 separate breath-holds, the implemented 3D-cine sequence allows for whole heart coverage in 1-2 breath-holds. The 4D-flow sequence allows for whole-chest coverage in less than 10 minutes. Finally, SENC imaging reduces scan time to only one slice per heartbeat. In conclusion, the proposed rapid, contrast-free, and comprehensive cardiovascular exam does not require repeated breath-holds or to be supervised by a cardiac imager. These improvements make it tolerable by patients and would help improve cost effectiveness of CMR and increase its adoption in clinical practice.

Identifiers

PMID34054936
PMCPMC8147553
OpenAlexW3163345646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.