ArticleFrontiers in plant science2021
Metabolome and Transcriptome Integration Reveals Insights Into Flavor Formation of 'Crimson' Watermelon Flesh During Fruit Development.
Article in Frontiers in plant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 45 citations in OpenAlex.
- Transcriptomic and biochemical insights into LOX pathway aroma biosynthesis during ripening ofFood chemistry. Molecular sciences · 2026Article
- Involvement of the LcARF17- and LcRAP2-4-LcLOX7 regulatory modules in the biosynthesis of fresh aroma in litchi aril.Horticulture research · 2026Article
- Genome-wide identification of the GATA transcription factor family in ten Cucurbitaceae species and expression analysis of ClGATA genes in watermelon stress responses.BMC genomics · 2026Article
- The DIR Gene Family in Watermelon: Evolution, Stress Expression Profiles, and Functional Exploration ofInternational journal of molecular sciences · 2025Article
- Detection and comparative analysis of VOCs between tomato and pepper based on GC×GC-TOFMS.Scientific reports · 2025Article
- Fresh-cut watermelon: postharvest physiology, technology, and opportunities for quality improvement.Frontiers in genetics · 2025Review
- Watermelon fruit metabolome gene discovery and its application in breeding: a review.Frontiers in plant science · 2025Review
- Integrated Transcriptome and Metabolome Analysis Reveals Molecular Mechanisms Underlying Resistance toPlants (Basel, Switzerland) · 2024Article
- Comparative Analysis of Metabolic Variation in Eggplant Fruit of Different Varieties Reveals Metabolites Important for Quality Traits.Foods (Basel, Switzerland) · 2023Article
- Integrative analysis of the metabolome and transcriptome reveals the potential mechanism of fruit flavor formation in wild hawthorn (Plant diversity · 2023Article
- Metabolomic approach for phytochemical assessment ofHeliyon · 2023Article
- Analysis of Volatile Aroma Components and Regulatory Genes in Different Kinds and Development Stages of Pepper Fruits Based on Non-Targeted Metabolome Combined with Transcriptome.International journal of molecular sciences · 2023Article
- Combined Metabolome and Transcriptome Analysis Elucidates Sugar Accumulation in Wucai (International journal of molecular sciences · 2023Article
- Metabolomic and transcriptomic analyses reveal the effects of grafting on blood orange quality.Frontiers in plant science · 2023Article
- Transcriptomic and Metabolomic Analyses Provide Insights into the Formation of the Peach-like Aroma ofGenes · 2022Article
- Article
- Genetic Analysis of Fruit Quality Traits in Sweet Watermelon (Frontiers in plant science · 2022Review
- Genome-wide association study provides genetic insights into natural variation in watermelon rind thickness and single fruit weight.Frontiers in plant science · 2022Article
- UPLC-MS/MS Profile Combined With RNA-Seq Reveals the Amino Acid Metabolism inFrontiers in nutrition · 2022Article
- An integrated metabolome and transcriptome approach reveals the fruit flavor and regulatory network during jujube fruit development.Frontiers in plant science · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolites have been reported as the main factor that influences the fruit flavor of watermelon. But the comprehensive study on the dynamics of metabolites during the development of watermelon fruit is not up-to-date. In this study, metabolome and transcriptome datasets of 'Crimson' watermelon fruit at four key developmental stages were generated. A total of 517 metabolites were detected by ultrahigh-performance liquid chromatography-electrospray ionization-tandem mass spectrometry and gas chromatography-solid-phase microextraction-mass spectrometry. Meanwhile, by K-means clustering analysis, the total differentially expressed genes were clustered in six classes. Integrating transcriptome and metabolome data revealed similar expression trends of sugars and genes involved in the glycolytic pathway, providing molecular insights into the formation of taste during fruit development. Furthermore, through coexpression analysis, we identified five differentially expressed ADH (alcohol dehydrogenase) genes (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.