Evidence map›Paper›PMID 34054843›Full record

ArticleFrontiers in immunology2021

Medicinal Plant Leaf Extract From Sage and Lemon Verbena Promotes Intestinal Immunity and Barrier Function in Gilthead Seabream (

Ricardo Salomón, Felipe E Reyes-López, Lluis Tort, Joana P Firmino, Carmen Sarasquete, Juan B Ortiz-Delgado, José C Quintela, José M Pinilla-Rosas, Eva Vallejos-Vidal, Enric Gisbert

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. An Ethnopharmacological Survey on Medicinally Important Plants of Genus Salvia.Combinatorial chemistry & high throughput screening · 2025
    Review
  3. DietaryFrontiers in microbiology · 2025
    Article
  4. Article
  5. Article
  6. Verbascoside-Rich Plant Extracts in Animal Nutrition.Antioxidants (Basel, Switzerland) · 2023
    Review
  7. Natural Compounds ofBiomedicines · 2023
    Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ricardo SalomónAquaculture Program, Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Sant Carles de la Ràpita (IRTA-SCR), Sant Carles de la Ràpita, Spain.
Felipe E Reyes-LópezDepartment of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Lluis TortDepartment of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Joana P FirminoAquaculture Program, Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Sant Carles de la Ràpita (IRTA-SCR), Sant Carles de la Ràpita, Spain.
Carmen SarasqueteInstituto de Ciencias Marinas de Andalucía (ICMAN-CSIC), Universidad de Cádiz, Cádiz, Spain.
Juan B Ortiz-DelgadoInstituto de Ciencias Marinas de Andalucía (ICMAN-CSIC), Universidad de Cádiz, Cádiz, Spain.
José C QuintelaNatac Biotech, Madrid, Spain.
José M Pinilla-RosasNatac Biotech, Madrid, Spain.
Eva Vallejos-VidalCentro de Biotecnología Acuícola, Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Enric GisbertAquaculture Program, Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Sant Carles de la Ràpita (IRTA-SCR), Sant Carles de la Ràpita, Spain.
Universitat Autònoma de Barcelona · ESInstitute for Research and Technology in Food and Agriculture · ESInstituto de Ciencias Marinas de Andalucía · ESUniversidad de Santiago de Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inclusion of a medicinal plant leaf extract (MPLE) from sage (

Indexed as

Salvia officinalisSea BreamVerbenaceaeAdherens JunctionsAnimalsCell DifferentiationGoblet CellsImmunity, MucosalImmunologic FactorsIntercellular JunctionsIntestinal MucosaLymphocyte ActivationMucinsPermeabilityPlant ExtractsPlant LeavesImmunologic FactorsMucinsPlant Extractscell proliferationfeed additiveGALTgut healthinnate immunitylectin histochemistryursolic acidverbascoside acid

Identifiers

PMID34054843
PMCPMC8160519
OpenAlexW3162525410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.