Evidence map›Paper›PMID 34054783›Full record

ArticleFrontiers in microbiology2021

On-Site Genomic Epidemiological Analysis of Antimicrobial-Resistant Bacteria in Cambodia With Portable Laboratory Equipment.

Aki Hirabayashi, Hideji Yanagisawa, Hiromizu Takahashi, Koji Yahara, Philipp Boeing, Bethan Wolfenden, Vandarith Nov, Vichet Lorn, Mom Veng, Vuth Ann and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  3. Article
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  6. Article
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  8. Molecular Typing of UkrainianMicroorganisms · 2022
    Article
  9. Avian strains of emerging pathogenFrontiers in microbiology · 2022
    Article
  10. A clinical KPC-producingFrontiers in microbiology · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Aki HirabayashiAMR Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Hideji YanagisawaMicroSKY Lab., Inc., Tokyo, Japan.
Hiromizu TakahashiDepartment of General Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Koji YaharaAMR Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Philipp BoeingBento Bioworks Ltd., London, United Kingdom.
Bethan WolfendenBento Bioworks Ltd., London, United Kingdom.
Vandarith NovNational Institute of Public Health, Phnom Penh, Cambodia.
Vichet LornNational Institute of Public Health, Phnom Penh, Cambodia.
Mom VengNational Institute of Public Health, Phnom Penh, Cambodia.
Vuth AnnNational Institute of Public Health, Phnom Penh, Cambodia.
Chau DarapheakNational Institute of Public Health, Phnom Penh, Cambodia.
Keigo ShibayamaDepartment of Bacteriology II, National Institute of Infectious Diseases, Tokyo, Japan.
Masato SuzukiAMR Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
National Institute of Public Health · KHNational Institute of Infectious Diseases · JPJuntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid emergence of carbapenemase-producing gram-negative bacteria (CPGNB) is a global threat due to the high mortality of infection and limited treatment options. Although there have been many reports of CPGNB isolated from Southeast Asian countries, to date there has been no genetic analysis of CPGNB isolated from Cambodia. Sequence-based molecular epidemiological analysis enables a better understanding of the genotypic characteristics and epidemiological significance of antimicrobial-resistant (AMR) bacteria in each country, and allows countries to enact measures related to AMR issues. In this study, we performed on-site genomic epidemiological analysis of CPGNB isolated in Cambodia using a portable laboratory equipment called Bento Lab, which combines a PCR thermal cycler, microcentrifuge, gel electrophoresis apparatus, and LED transilluminator, along with the MinION nanopore sequencer. PCR targeting of major carbapenemase genes using Bento Lab revealed that two

Indexed as

AcinetobacterAMRCambodiacarbapenemaseCPE

Identifiers

PMID34054783
PMCPMC8158813
OpenAlexW3162000870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.