ArticleFrontiers in physiology2021
Development of a Novel Web Camera-Based Contact-Free Major Depressive Disorder Screening System Using Autonomic Nervous Responses Induced by a Mental Task and Its Clinical Application.
Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Contactless depression screening via facial video-derived heart rate variability.Translational psychiatry · 2026Article
- Remote photoplethysmography for health assessment: a review informed by IntelliProve technology.Frontiers in digital health · 2025Review
- The Use of Photoplethysmography in the Assessment of Mental Health: Scoping Review.JMIR mental health · 2023Article
- Screening for Major Depressive Disorder Using a Wearable Ultra-Short-Term HRV Monitor and Signal Quality Indices.Sensors (Basel, Switzerland) · 2023Article
- Clinical applications of contactless photoplethysmography for monitoring in adults: A systematic review and meta-analysis.Journal of clinical and translational science · 2023Review
- Multi-ROI Spectral Approach for the Continuous Remote Cardio-Respiratory Monitoring from Mobile Device Built-In Cameras.Sensors (Basel, Switzerland) · 2022Article
- Resting-state EEG-based convolutional neural network for the diagnosis of depression and its severity.Frontiers in physiology · 2022Article
- Development of a Novel Vital-Signs-Based Infection Screening Composite-Type Camera With Truncus Motion Removal Algorithm to Detect COVID-19 Within 10 Seconds and Its Clinical Validation.Frontiers in physiology · 2022Article
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo increase the consultation rate of potential major depressive disorder (MDD) patients, we developed a contact-type fingertip photoplethysmography-based MDD screening system. With the outbreak of SARS-CoV-2, we developed an alternative to contact-type fingertip photoplethysmography: a novel web camera-based contact-free MDD screening system (WCF-MSS) for non-contact measurement of autonomic transient responses induced by a mental task.
methodsThe WCF-MSS measures time-series interbeat intervals (IBI) by monitoring color tone changes in the facial region of interest induced by arterial pulsation using a web camera (1920 × 1080 pixels, 30 frames/s). Artifacts caused by body movements and head shakes are reduced. The WCF-MSS evaluates autonomic nervous activation from time-series IBI by calculating LF (0.04-0.15 Hz) components of heart rate variability (HRV) corresponding to sympathetic and parasympathetic nervous activity and HF (0.15-0.4 Hz) components equivalent to parasympathetic activities. The clinical test procedure comprises a pre-rest period (Pre-R; 140 s), mental task period (MT; 100 s), and post-rest period (Post-R; 120 s). The WCF-MSS uses logistic regression analysis to discriminate MDD patients from healthy volunteers via an optimal combination of four explanatory variables determined by a minimum redundancy maximum relevance algorithm: HF during MT (HF
resultThe WCF-MSS achieved 73% sensitivity and 85% specificity on 5-fold cross-validation. IBI correlated significantly with IBI from reference electrocardiography (
conclusionThe WCF-MSS seems a promising contact-free MDD screening apparatus. This method enables web camera built-in smartphones to be used as MDD screening systems.
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