Evidence map›Paper›PMID 34054541›Full record

ArticleFrontiers in pharmacology2021

Shaoyao-Gancao Decoction Ameliorates the Inflammation State in Polycystic Ovary Syndrome Rats via Remodeling Gut Microbiota and Suppressing the TLR4/NF-κB Pathway.

Zhuang-Peng Chang, Gui-Feng Deng, Yun-Yun Shao, Ding Xu, Yi-Nan Zhao, Yi-Fan Sun, Shi-Quan Zhang, Rui-Gang Hou, Jun-Jin Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
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  13. Shaoyao Gancao decoction alleviates functional constipation by inhibitingFrontiers in cellular and infection microbiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhuang-Peng ChangSchool of Pharmaceutical, Shanxi Medical University, Taiyuan, China.
Gui-Feng DengSchool of Pharmaceutical, Shanxi Medical University, Taiyuan, China.
Yun-Yun ShaoSchool of Pharmaceutical, Shanxi Medical University, Taiyuan, China.
Ding XuSchool of Pharmaceutical, Shanxi Medical University, Taiyuan, China.
Yi-Nan ZhaoSchool of Pharmaceutical, Shanxi Medical University, Taiyuan, China.
Yi-Fan SunSchool of Pharmaceutical, Shanxi Medical University, Taiyuan, China.
Shi-Quan ZhangSchool of Pharmaceutical, Shanxi Medical University, Taiyuan, China.
Rui-Gang HouSchool of Pharmaceutical, Shanxi Medical University, Taiyuan, China.
Jun-Jin LiuSchool of Pharmaceutical, Shanxi Medical University, Taiyuan, China.
Shanxi Medical University · CNSecond Hospital of Shanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

gut barriergut microbiotapolycystic ovary syndromeshaoyao-gancao decoctionTLR4/NF-κB pathway

Identifiers

PMID34054541
PMCPMC8155368
OpenAlexW3161201997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.