Evidence map›Paper›PMID 34054520›Full record

ArticleFrontiers in pharmacology2021

Neuroprotective and Angiogenesis Effects of Levetiracetam Following Ischemic Stroke in Rats.

Xiang Yao, Wenping Yang, Zhendong Ren, Haoran Zhang, Dafa Shi, Yanfei Li, Ziyang Yu, Qiu Guo, Guangwei Yang, Yingjiang Gu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Targeting angiogenesis and white matter repair for enhanced functional recovery after acute ischemic stroke: A focus on the roles of glial cells.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Impact of levetiracetam on cognitive impairment, neuroinflammation, oxidative stress, and neuronal apoptosis caused by lipopolysaccharides in rats.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  8. Article
  9. Article
  10. The Effect of a NewMolecules (Basel, Switzerland) · 2022
    Article
  11. Review
  12. Levetiracetam Mechanisms of Action: From Molecules to Systems.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Xiang YaoDepartment of Radiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Wenping YangDivision of Neurology, Department of Geriatrics, Jiangsu Province Hospital, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zhendong RenDepartment of Radiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Haoran ZhangDepartment of Radiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Dafa ShiDepartment of Radiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Yanfei LiDepartment of Radiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Ziyang YuDepartment of Radiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Qiu GuoDepartment of Radiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Guangwei YangHospital (T.C.M) Affiliated to Southwest Medical University, Luzhou, China.
Yingjiang GuHospital (T.C.M) Affiliated to Southwest Medical University, Luzhou, China.
Hairong ZhaoSchool of Medicine, Xiamen University, Xiamen, China.
Ke RenDepartment of Radiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Xiamen University · CNSouthwest Medical University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

heat shock protein 70hypoxia-inducible factorischemic strokelevetiracetamneuroprotectionvascular endothelial growth factor

Identifiers

PMID34054520
PMCPMC8161206
OpenAlexW3160743591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.