ArticleFrontiers in behavioral neuroscience2021
Fatigue After Aneurysmal Subarachnoid Hemorrhage: Clinical Characteristics and Associated Factors in Patients With Good Outcome.
Article in Frontiers in behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Incidence and related risk factors of post-stroke fatigue in patients with hemorrhagic stroke: a systematic review and meta-analysis.BMC neurology · 2026Pooled it
- Cognition and Health-Related Quality of Life After aSAH: The Role of Objective and Subjective Impairment.Neurology international · 2026Article
- When blood hits the brain: altered glymphatic and dural lymphatic function after surface bleeds.Acta neurochirurgica · 2026Article
- C-reactive protein and fatigue after subarachnoid haemorrhage.Brain, behavior, & immunity - health · 2025Article
- Comparative analysis of surgical and endovascular aneurysm repair in subarachnoid hemorrhage: a single-center study with 1,171 patients.Acta neurochirurgica · 2025Article
- Health-related quality of life after spontaneous subarachnoid hemorrhage - a prospective cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Mindfulness-based stress reduction as perceived by individuals with pathological mental fatigue after an acquired brain injury.Scientific reports · 2025Article
- The urotensin II receptor triggers an early meningeal response and a delayed macrophage-dependent vasospasm after subarachnoid hemorrhage in male mice.Nature communications · 2024Article
- Occupational performance one to five years after aneurysmal subarachnoid haemorrhage: a cohort study.Journal of rehabilitation medicine · 2024Article
- Return to work after aneurysmal subarachnoid hemorrhage.Frontiers in neurology · 2024Article
- The relationship between mental fatigue, depression, and cognition in Graves' disease.European thyroid journal · 2023Article
- Coping strategies in patients with good outcome but chronic fatigue after aneurysmal subarachnoid hemorrhage.Acta neurochirurgica · 2023Article
- Long-term fatigue following aneurysmal subarachnoid haemorrhage and the impact on employment.European journal of neurology · 2022Observational
- Long-term outcomes after aneurysmal subarachnoid hemorrhage: A prospective observational cohort study.Acta neurologica Scandinavica · 2022Observational
- The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implications.The Biochemical journal · 2022Review
- Screening Method for Assessment of Work Ability for Patients Suffering From Mental Fatigue.Frontiers in behavioral neuroscience · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fatigue after aneurysmal subarachnoid hemorrhage (post-aSAH fatigue) is a frequent, often long-lasting, but still poorly studied sequel. The aim of the present study was to characterize the nature of post-aSAH fatigue with an itemized analysis of the Fatigue Severity Scale (FSS) and Mental Fatigue Scale (MFS). We further wanted to assess the association of fatigue with other commonly observed problems after aSAH: mood disorders, cognitive problems, health-related quality of life (HRQoL), weight gain, and return to work (RTW). Ninety-six good outcome aSAH patients with fatigue completed questionnaires measuring fatigue, depression, anxiety, and HRQoL. All patients underwent a physical and neurological examination. Cognitive functioning was assessed with a neuropsychological test battery. We also registered prior history of fatigue and mood disorders as well as occupational status and RTW. The patients experienced fatigue as being among their three most disabling symptoms and when characterizing their fatigue they emphasized the questionnaire items "low motivation," "mental fatigue," and "sensitivity to stress." Fatigue due to exercise was their least bothersome aspect of fatigue and weight gain was associated with depressive symptoms rather than the severity of fatigue. Although there was a strong association between fatigue and mood disorders, especially for depression, the overlap was incomplete. Post-aSAH fatigue related to reduced HRQoL. RTW was remarkably low with only 10.3% of patients returning to their previous workload. Fatigue was not related to cognitive functioning or neurological status. Although there was a strong association between fatigue and depression, the incomplete overlap supports the notion of these two being distinct constructs. Moreover, post-aSAH fatigue can exist without significant neurological or cognitive impairments, but is related to reduced HRQoL and contributes to the low rate of RTW.
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