ReviewFrontiers in neuroscience2021
Neurostimulation for Stroke Rehabilitation.
Review in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Enhancing functional motor outcomes in chronic stroke: A systematic review of the growing role of non-invasive brain stimulation.PloS one · 2025Pooled it
- Effects of home-based neurostimulation on outcomes after stroke: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Pooled it
- Combining Robot-Assisted Gait Training and Non-Invasive Brain Stimulation in Chronic Stroke Patients: A Systematic Review.Frontiers in neurology · 2022Pooled it
- From optical control to translational readiness: an evidence-tiered framework for optogenetics in neuromuscular and neurological disorders.Materials today. Bio · 2026Review
- Motor Recovery After a Hemispherectomy: Review of Mechanisms and the Potential of Neuromodulation to Enhance Motor Outcomes.Journal of child neurology · 2026Review
- Breathing-driven modulation of reticulospinal tract activity.Experimental physiology · 2026Article
- Corticomuscular coherence and its non-invasive modulation in stroke applications: a narrative review.Neuroimage. Reports · 2026Article
- Acupuncture as an Adjunct to Physiotherapy in Post-Stroke Spastic Hand: Comparative Case Series Analysis.Cureus · 2026Article
- Bilateral transcutaneous auricular nerve stimulation promotes motor function recovery after stroke: A randomized controlled trial.Therapeutic advances in neurological disorders · 2026Article
- Combining nonlinear mechanical stimulation via a chaotic mathematical model and game-based exercise for upper extremity rehabilitation in children with spastic hemiparetic cerebral palsy: a pilot study.Biomedical engineering online · 2025Article
- Closed-loop Neuromotor Training System Pairing Transcutaneous Vagus Nerve Stimulation with Video-based Real-time Movement Classification.medRxiv : the preprint server for health sciences · 2025Article
- Hybrid Electro-optical Stimulation Improves Ischemic Brain Damage by Augmenting the Glymphatic System.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Dynamic electrophysiological changes in abnormal brain cavities post-ischemic stroke.Frontiers in neuroscience · 2025Article
- Harnessing theta waves: tACS as a breakthrough in alleviating post-stroke chronic pain.Frontiers in neuroscience · 2025Review
- Spreading Depolarization Induces a Transient Potentiation of Excitatory Synaptic Transmission.Neuroscience · 2024Article
- 1953-2023. Seventy Years of the Nerve Growth Factor: A Potential Novel Treatment in Neurological Diseases?Aging and disease · 2024Review
- Effects of Cerebellar Non-Invasive Stimulation on Neurorehabilitation in Stroke Patients: An Updated Systematic Review.Biomedicines · 2024Review
- Innovation at the Intersection: Emerging Translational Research in Neurology and Psychiatry.Cells · 2024Article
- The evolution of neuromodulation for chronic stroke: From neuroplasticity mechanisms to brain-computer interfaces.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024Review
- Closed-Loop Brain Stimulation.Biological psychiatry · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurological injuries such as strokes can lead to important loss in motor function. Thanks to neuronal plasticity, some of the lost functionality may be recovered over time. However, the recovery process is often slow and incomplete, despite the most effective conventional rehabilitation therapies. As we improve our understanding of the rules governing activity-dependent plasticity, neuromodulation interventions are being developed to harness neural plasticity to achieve faster and more complete recovery. Here, we review the principles underlying stimulation-driven plasticity as well as the most commonly used stimulation techniques and approaches. We argue that increased spatiotemporal precision is an important factor to improve the efficacy of neurostimulation and drive a more useful neuronal reorganization. Consequently, closed-loop systems and optogenetic stimulation hold theoretical promise as interventions to promote brain repair after stroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.