Evidence map›Paper›PMID 34054407›Full record

ArticleFrontiers in neuroscience2021

Chunlan Liu, Qiming Yin, Mengxia Li, Yao Fan, Chong Shen, Rongxi Yang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. β-Actin: An Emerging Biomarker in Ischemic Stroke.Cellular and molecular neurobiology · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. The association betweenFrontiers in cardiovascular medicine · 2022
    Article
  11. [Association betweenNan fang yi ke da xue xue bao = Journal of Southern Medical University
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chunlan LiuDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Qiming YinDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Mengxia LiDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Yao FanDivision of Clinical Epidemiology, Affiliated Geriatric Hospital of Nanjing Medical University, Nanjing, China.
Chong ShenDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Rongxi YangDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStroke is the second leading cause of death worldwide. If risk of stroke could be evaluated early or even at a preclinical stage, the mortality rate could be reduced dramatically. However, the identified genetic factors only account for 5-10% of the risk of stroke. Studies on the risk factors of stroke are urgently needed. We investigated the correlation between blood-based β-actin (

methodsThe methylation level of

resultsWe observed a highly significant correlation between hypomethylation of one CpG site of

conclusionWe firstly reported the blood-based

Indexed as

ACTB geneDNA methylationmarkerpre-clinical detectionstroke

Identifiers

PMID34054407
PMCPMC8160447
OpenAlexW3162806772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.