Evidence map›Paper›PMID 34054331›Full record

ArticleChemical engineering journal (Lausanne, Switzerland : 1996)2021

Self-assembling Peptide Hydrogels Facilitate Vascularization in Two-Component Scaffolds.

Zain Siddiqui, Biplab Sarkar, Ka Kyung Kim, Arjun Kumar, Reshma Paul, Aryan Mahajan, Jonathan M Grasman, Jian Yang, Vivek A Kumar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical engineering journal (Lausanne, Switzerland : 1996), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zain Siddiqui *Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Biplab Sarkar *Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Ka Kyung KimDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Arjun KumarDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Reshma PaulDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Aryan MahajanDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Jonathan M GrasmanDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Jian YangDepartment of Biomedical Engineering, Huck Institutes of The Life Sciences, Materials Research Institute, Pennsylvania State University, University Park, PA, USA.
Vivek A KumarDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.

Funding

Citrate Metabonegenic Regulation for the next Generation of Orthopedic Biomaterial DesignR01AR072731 · NIAMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI YANG, JIAN · 2018 to 2022
$1.7M
Peptide hydrogels for management and treatment of neovascular posterior segment diseasesR15EY029504 · NEI · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI KUMAR, VIVEK · 2019 to 2020
$508k
NEI NIH HHS R15 EY029504NIAMS NIH HHS R01 AR072731
6 · The paper itself

Abstract

One of the major constraints against using polymeric scaffolds as tissue-regenerative matrices is a lack of adequate implant vascularization. Self-assembling peptide hydrogels can sequester small molecules and biological macromolecules, and they can support infiltrating cells

Indexed as

acellular scaffoldsangiogenesishydrogelimplant vascularizationmulti-functional scaffoldspeptide nanofibersself-assemblytissue regeneration

Identifiers

PMID34054331
PMCPMC8158327

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.